Rabbit anti-Human FBXW10 Polyclonal Antibody | anti-FBXW10 antibody
FBXW10 Antibody, FITC conjugated
Gene Names
FBXW10; HREP; Fbw10; SM25H2; SM2SH2
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
FBXW10; Polyclonal Antibody; FBXW10 Antibody; FITC conjugated; F-box/WD repeat-containing protein 10; F-box and WD-40 domain-containing protein 10; Ubiquitin ligase-specificity factor; anti-FBXW10 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
1052
Applicable Applications for anti-FBXW10 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant human F-box/WD repeat-containing protein 10 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-164383
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-FBXW10 antibody
Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
119,774 Da
NCBI Official Full Name
F-box/WD repeat-containing protein 10 isoform 1
NCBI Official Synonym Full Names
F-box and WD repeat domain containing 10
NCBI Official Symbol
FBXW10
NCBI Official Synonym Symbols
HREP; Fbw10; SM25H2; SM2SH2
NCBI Protein Information
F-box/WD repeat-containing protein 10
UniProt Protein Name
F-box/WD repeat-containing protein 10
Protein Family
UniProt Gene Name
FBXW10
UniProt Entry Name
FBW10_HUMAN
NCBI Description
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Uniprot Description
Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
Research Articles on FBXW10
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Product Notes
The FBXW10 fbxw10 (Catalog #AAA1495761) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBXW10 Antibody, FITC conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FBXW10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the FBXW10 fbxw10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXW10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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