Testing Data
(Primary: Anti-FBXO25 at 1/1000 dilution)
Rabbit FBXO25 Polyclonal Antibody | anti-FBXO25 antibody
FBXO25 Polyclonal Antibody
Gene Names
FBXO25; FBX25; MGC20256; MGC51975
Reactivity
Human, Mouse, Rat, Pig, Rabbit
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
FBXO25; Polyclonal Antibody; FBXO25 Polyclonal Antibody; F box only protein 25; F box protein 25; F box protein Fbx25; F-box only protein 25; FBX25; MGC20256; MGC51975; OTTHUMP00000115399; anti-FBXO25 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig, Rabbit
Clonality
Polyclonal
Specificity
FBXO25 Polyclonal Antibody detects endogenous levels of FBXO25 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-FBXO25 antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human FBXO25:55-150/367
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
(Primary: Anti-FBXO25 at 1/1000 dilution)
Testing Data
(Primary: Anti-FBXO25 at 1/1000 dilution)
Testing Data
(Primary: Anti-FBXO25 at 1/500 dilution)
Testing Data
(Primary: Anti-FBXO25 at 1/500 dilution)
Related Product Information for anti-FBXO25 antibody
FBXO25 is a member of the F box protein family which is characterized by an approximately 40 amino acid motif, the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box), which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains, Fbls containing leucine rich repeats, and Fbxs containing either different protein protein interaction modules or no recognizable motifs. FBXO25 belongs to the Fbxs class. There are three named isoforms produced by alternative splicing.FBXO25, also known as FBX25, is a 367 amino acid protein that contains one C-terminal F-box domain and belongs to the Fbx class of the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Expressed at high levels in brain, FBXO25 localizes predominantly to the nucleus and directly interacts with Skp1 p19 and CUL-1. Disruption of the gene encoding FBXO25 can lead to X-linked mental retardation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,313 Da
NCBI Official Full Name
F-box only protein 25 isoform 1
NCBI Official Synonym Full Names
F-box protein 25
NCBI Official Symbol
FBXO25
NCBI Official Synonym Symbols
FBX25; MGC20256; MGC51975
NCBI Protein Information
F-box only protein 25; OTTHUMP00000115396; OTTHUMP00000115397; OTTHUMP00000115399; F-box protein Fbx25
UniProt Protein Name
F-box only protein 25
Protein Family
UniProt Gene Name
FBXO25
UniProt Synonym Gene Names
FBX25
UniProt Entry Name
FBX25_HUMAN
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Product Notes
The FBXO25 fbxo25 (Catalog #AAA3005582) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBXO25 Polyclonal Antibody reacts with Human, Mouse, Rat, Pig, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's FBXO25 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the FBXO25 fbxo25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXO25, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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