Western Blot (WB)
(Western blot analysis of extracts from NIH/3T3 cells using FBXL3 Antibody.)
Rabbit anti-Mouse FBXL3 Polyclonal Antibody | anti-FBXL3 antibody
FBXL3 Antibody
Gene Names
Fbxl3; FBK; Ovtm; Fbl3a; Fbxl3a; Play68; AU041772; AW212966
Reactivity
Mouse
Applications
Western Blot
Purity
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Synonyms
FBXL3; Polyclonal Antibody; FBXL3 Antibody; FBK; Ovtm; Fbl3a; AU041772; anti-FBXL3 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total FBXL3 protein.
Purity/Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
428
Applicable Applications for anti-FBXL3 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:1000
Immunogen Type
Peptide-KLH
Immunogen Description
Peptide sequence around aa.1~5 (M-K-R-G-G) derived from mouse FBXL3
Target Name
FBXL3
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.
Western Blot (WB)
(Western blot analysis of extracts from NIH/3T3 cells using FBXL3 Antibody.)
Western Blot (WB)
(Western blot analysis of extracts from NIH/3T3 cells using FBXL3 Antibody.)
Related Product Information for anti-FBXL3 antibody
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
Product Categories/Family for anti-FBXL3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,857 Da
NCBI Official Full Name
F-box/LRR-repeat protein 3
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 3
NCBI Official Symbol
Fbxl3
NCBI Official Synonym Symbols
FBK; Ovtm; Fbl3a; Fbxl3a; Play68; AU041772; AW212966
NCBI Protein Information
F-box/LRR-repeat protein 3
UniProt Protein Name
F-box/LRR-repeat protein 3
UniProt Gene Name
Fbxl3
UniProt Synonym Gene Names
Afh; Fbl3a; Fbxl3a; Ovtm
UniProt Entry Name
FBXL3_MOUSE
Uniprot Description
FBXL3: Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Protein type: Ubiquitin conjugating system
Cellular Component: nucleoplasm; cytoplasm; SCF ubiquitin ligase complex; cytosol; nucleus
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; protein destabilization; rhythmic process; protein ubiquitination; regulation of circadian rhythm; entrainment of circadian clock by photoperiod
Research Articles on FBXL3
Similar Products
Product Notes
The FBXL3 fbxl3 (Catalog #AAA9410850) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBXL3 Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FBXL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:1000. Researchers should empirically determine the suitability of the FBXL3 fbxl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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