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Rabbit FBXL18 Polyclonal Antibody | anti-FBXL18 antibody

FBXL18

Gene Names
FBXL18; Fbl18
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
FBXL18; Polyclonal Antibody; Purified Rabbit Anti Human FBXL18 Polyclonal antibody; Fbl18; anti-FBXL18 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2100
Applicable Applications for anti-FBXL18 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 5-167aa of human FBXL18.
Related Product Information for anti-FBXL18 antibody
Homo sapiens F-box and leucine-rich repeat protein 18, mRNA
References
Jin J, Cardozo T, Lovering R C. et al. Systematic analysis and nomenclature of mammalian F-box proteins. Genes & development. 18 (21):2573-2580 (2004)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
88kDa
NCBI Official Full Name
Homo sapiens F-box and leucine-rich repeat protein 18, mRNA
NCBI Official Synonym Full Names
F-box and leucine rich repeat protein 18
NCBI Official Symbol
FBXL18
NCBI Official Synonym Symbols
Fbl18
NCBI Protein Information
F-box/LRR-repeat protein 18
Protein Family

NCBI Description

The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016]

Research Articles on FBXL18

Similar Products

Product Notes

The FBXL18 (Catalog #AAA8563970) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBXL18 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FBXL18 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20000-80000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the FBXL18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXL18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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