Rabbit FBXL16 Polyclonal Antibody | anti-FBXL16 antibody

FBXL16 Antibody

Cat. Num. AAA150124

• Gene Names: FBXL16; Fbl16; C16orf22; c380A1.1
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: FBXL16 Antibody is affinity chromatography purified via peptide column.
• Synonyms: FBXL16; Polyclonal Antibody; FBXL16 Antibody; Fbl16; C16orf22; c380A1.1; FBL16; F-box and leucine-rich repeat protein 16; anti-FBXL16 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: FBXL16 antibody is predicted to not cross-react with other F-box protein family members.
• Purity/Purification: FBXL16 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 479

• Applicable Applications for anti-FBXL16 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: FBXL16 antibody can be used for detection of FBXL16 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL.
• Conjugate: Unconjugated
• Immunogen: FBXL16 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human FBXL16
• Buffer: FBXL16 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: FBXL16 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of FBXL16 in human spleen tissue lysate with FBXL16 antibody at (A) 0.5 and (B) 1 μg/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of FBXL16 in human spleen tissue with FBXL16 antibody at 5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of FBXL16 in human spleen tissue with FBXL16 antibody at 20 μg/mL.)

Related Product Information for anti-FBXL16 antibody

FBXL16 Antibody: FBXL16 (F-box and leucine-rich repeat protein 16), a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F-box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.

NCBI and Uniprot Product Information

• NCBI GI #: 289666746
• NCBI GeneID: 146330
• NCBI Accession #: NP_699181
• NCBI GenBank Nucleotide #: NM_153350.3
• UniProt Accession #: Q8N461; Q2MHR2; Q96S14; Q9UJI0; B3KR59; D3DU60
• Molecular Weight: 29,423 Da
• NCBI Official Full Name: F-box/LRR-repeat protein 16
• NCBI Official Synonym Full Names: F-box and leucine-rich repeat protein 16
• NCBI Official Symbol: FBXL16
• NCBI Official Synonym Symbols: Fbl16; C16orf22; c380A1.1
• NCBI Protein Information: F-box/LRR-repeat protein 16; c380A1.1 (novel protein)
• UniProt Protein Name: F-box/LRR-repeat protein 16
• UniProt Gene Name: FBXL16
• UniProt Synonym Gene Names: C16orf22; FBL16
• UniProt Entry Name: FXL16_HUMAN

NCBI Description

Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

Uniprot Description

FBXL16: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cytoplasm