Rabbit anti-Human FASTK Polyclonal Antibody | anti-FASTK antibody

FASTK (Fas-Activated Serine/Threonine Kinase, FAST) (AP)

Cat. Num. AAA6450937

• Gene Names: FASTK; FAST
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified
• Synonyms: FASTK; Polyclonal Antibody; FASTK (Fas-Activated Serine/Threonine Kinase; FAST) (AP); Fas-Activated Serine/Threonine Kinase; FAST; anti-FASTK antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FASTK.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-FASTK antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: FASTK (NP_006703.1, 1aa-549aa) full-length human protein.
• Immunogen Sequence: MRRPRGEPGPRAPRPTEGATCAGPGESWSPSPNSMLRVLLSAQTSPARLSGLLLIPPVQPCCLGPSKWGDRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRPRPPPVEQVTLQDLSQLIIRNCPSFDIHTIHVCLHLAVLLGFPSDGPLVCALEQERRLRLPPKPPPPLQPLLRGGQGLEAALSCPRFLRYPRQHLISSLAEARPEELTPHVMVLLAQHLARHRLREPQLLEAIAHFLVVQETQLSSKVVQKLVLPFGRLNYLPLEQQFMPCLERILAREAGVAPLATVNILMSLCQLRCLPFRALHFVFSPGFINYISGTPHALIVRRYLSLLDTAVELELPGYRGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEEKYRQDLTVPPGYCTDFLLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGLPQLKSYLRQKLQALGLRWGPEGG
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of FASTK expression in transfected 293T cell line by FASTK MaxPab polyclonal antibody.Lane 1: FASTK transfected lysate(61.10 KDa).Lane 2: Non-transfected lysate.)

Related Product Information for anti-FASTK antibody

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq]

Product Categories/Family for anti-FASTK antibody

Antibodies; Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 5729822
• NCBI GeneID: 10922
• NCBI Accession #: NP_006703.1
• NCBI GenBank Nucleotide #: NM_006712.4
• UniProt Accession #: Q14296; Q59EM8; Q8IVA0; A8K867; F8VTW9
• Molecular Weight: 57,576 Da
• NCBI Official Full Name: fas-activated serine/threonine kinase isoform 1
• NCBI Official Synonym Full Names: Fas activated serine/threonine kinase
• NCBI Official Symbol: FASTK
• NCBI Official Synonym Symbols: FAST
• NCBI Protein Information: fas-activated serine/threonine kinase
• UniProt Protein Name: Fas-activated serine/threonine kinase
• Protein Family: Fas-activated serine/threonine kinase
• UniProt Gene Name: FASTK
• UniProt Synonym Gene Names: FAST kinase
• UniProt Entry Name: FASTK_HUMAN

NCBI Description

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]