Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Family With Sequence Similarity 5 Polyclonal Antibody | anti-FAM5C antibody
Polyclonal Antibody to Family With Sequence Similarity 5, Member C (FAM5C)
Gene Names
BRINP3; FAM5C; DBCCR1L; DBCCR1L1
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography.
Synonyms
Family With Sequence Similarity 5; Polyclonal Antibody; Polyclonal Antibody to Family With Sequence Similarity 5; Member C (FAM5C); anti-FAM5C antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against FAM5C. It has been selected for its ability to recognize FAM5C in immunohistochemical staining and western blotting.
Purity/Purification
Affinity Chromatography.
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence Length
783
Applicable Applications for anti-FAM5C antibody
WB, ICC, IHC-P, IHC-F, ELISA
Application Notes
Western blotting: 1:50-400
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.
Immunocytochemistry in formalin fixed cells: 1:50-500
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Immunohistochemistry in paraffin section: 1:10-100
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user.
Immunogen
FAM5C, Human
Immunogen Information
Recombinant FAM5C (Arg74~Ala264) with two N-terminal Tags, His-tag and T7-tag expressed in E.coli.
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant FAM5C (Arg74~Ala264) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2085126
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
76,299 Da
NCBI Official Full Name
BMP/retinoic acid-inducible neural-specific protein 3 isoform 2
NCBI Official Synonym Full Names
BMP/retinoic acid inducible neural specific 3
NCBI Official Symbol
BRINP3
NCBI Official Synonym Symbols
FAM5C; DBCCR1L; DBCCR1L1
NCBI Protein Information
BMP/retinoic acid-inducible neural-specific protein 3
UniProt Protein Name
BMP/retinoic acid-inducible neural-specific protein 3
UniProt Gene Name
BRINP3
UniProt Synonym Gene Names
DBCCR1L; DBCCR1L1; FAM5C
NCBI Description
This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Uniprot Description
FAM5C: Belongs to the FAM5 family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1q31.1
Cellular Component: cell soma; dendrite; endoplasmic reticulum; extracellular region; mitochondrion
Biological Process: cell cycle arrest; negative regulation of mitotic cell cycle; positive regulation of neuron differentiation
Research Articles on FAM5C
Similar Products
Product Notes
The FAM5C brinp3 (Catalog #AAA2026401) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Family With Sequence Similarity 5, Member C (FAM5C) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Family With Sequence Similarity 5 can be used in a range of immunoassay formats including, but not limited to, WB, ICC, IHC-P, IHC-F, ELISA. Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-200 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the FAM5C brinp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Family With Sequence Similarity 5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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