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Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Rabbit anti-Pig F8/FVIII/Factor VIII Polyclonal Antibody | anti-F8 antibody

Anti-F8/FVIII/Factor VIII Antibody (aa1669-1824)

Gene Names
F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E
Reactivity
Pig
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Affinity Purified
Synonyms
F8/FVIII/Factor VIII; Polyclonal Antibody; Anti-F8/FVIII/Factor VIII Antibody (aa1669-1824); Sheep Polyclonal (IgG) to Human F8/FVIII/Factor VIII; F8; AHF; Antihemophilic factor; Coagulation factor VIIIc; Coagulation factor VIII; DXS1253E; Factor VIII F8B; FVIII; HEMA; F8B; Factor VIII; Procoagulant component; F8C; anti-F8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Pig
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Sequence Length
2351
Applicable Applications for anti-F8 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB)
Application Notes
IHC-P: 1:50
Immunogen
Recombinant F8 (Gly1669-Ala1824) expressed in E. coli.
Conjugation
Unconjugated
Epitope
aa1669-1824
Preparation and Storage
Store frozen product at or below -20 degree C.
Thawed product may be stored for 2-4 weeks at 4 degree C.
For optimal storage, aliquot to smaller portions and store at -20 degree C to -70 degree C.
Avoid repeated freeze/thaw cycles.

Immunohistochemistry (IHC)

(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Immunohistochemistry (IHC) (Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Western Blot (WB)

(Western blot of recombinant F8/FVIII/Factor VIII. This image was taken for the unconjugated form of this product. Other forms have not been tested.)

Western Blot (WB) (Western blot of recombinant F8/FVIII/Factor VIII. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
Related Product Information for anti-F8 antibody
F8/FVIII/Factor VIII is coagulation factor VIII, which participatesin the intrinsic pathway of blood coagulation; factor VIII is acofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This geneproduces two alternatively spliced transcripts. Transcript variant 1encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebr and factor in a noncovalent complex.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,641 Da
NCBI Official Full Name
coagulation factor VIII isoform a preproprotein
NCBI Official Synonym Full Names
coagulation factor VIII
NCBI Official Symbol
F8
NCBI Official Synonym Symbols
AHF; F8B; F8C; HEMA; FVIII; DXS1253E
NCBI Protein Information
coagulation factor VIII
UniProt Protein Name
Coagulation factor VIII
Protein Family
UniProt Gene Name
F8
UniProt Synonym Gene Names
F8C; AHF

NCBI Description

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]

Uniprot Description

Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.

Research Articles on F8

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Product Notes

The F8 f8 (Catalog #AAA2401134) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-F8/FVIII/Factor VIII Antibody (aa1669-1824) reacts with Pig and may cross-react with other species as described in the data sheet. AAA Biotech's F8/FVIII/Factor VIII can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB). IHC-P: 1:50. Researchers should empirically determine the suitability of the F8 f8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "F8/FVIII/Factor VIII, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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