Western Blot (WB)
(Western blot analysis of extracts of human plasma cell and human platelet cell lines, using F5 antibody)
Rabbit anti-Human F5 Polyclonal Antibody | anti-F5 antibody
F5 Polyclonal Antibody
Gene Names
F5; FVL; PCCF; THPH2; RPRGL1
Reactivity
Human
Applications
Western Blot
Purity
Affinity purification
Synonyms
F5; Polyclonal Antibody; F5 Polyclonal Antibody; FVL; PCCF; Coagulation factor V light chain; Activated protein C cofactor ; Proaccelerin; labile factor ;; anti-F5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Sequence Length
2224
Applicable Applications for anti-F5 antibody
Western Blot (WB)
Application Notes
Western Blot (WB): 1:500-1:2000
Immunogen
A synthetic peptide of human F5
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C or -80 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of human plasma cell and human platelet cell lines, using F5 antibody)
Western Blot (WB)
(Western blot analysis of extracts of human plasma cell and human platelet cell lines, using F5 antibody)
Related Product Information for anti-F5 antibody
Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin, and factors X, IX, V, and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble fibrin clots and the promotion of platelet aggregation. Coagulation factor V (Factor V, FV, proaccelerin, labile factor) is a 2,196 amino acid, single chain glycoprotein that is cleaved by thrombin to yield an active, Ca2+ dependent dimer. This heterodimer is essential to the blood coagulation cascade. Together with catalytic Factor Xa and Ca2+ on the surface of platelets or endothelial cells, Factor Va coordinates in a prothrombinase complex, which mediates proteolysis of prothrombin into active thrombin. Due to both the procoagulant properties of Factor V in coordinating proteolytic activation of thrombin, and anticoagulant properties as a cofactor to activated protein C (APC), which selectively destroys FVa and FXa, alterations at the Factor V locus can contribute to hemorrhagic diathesis or thrombosis, respectively.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
330kDa
NCBI Official Full Name
coagulation factor V
NCBI Official Synonym Full Names
coagulation factor V (proaccelerin, labile factor)
NCBI Official Symbol
F5
NCBI Official Synonym Symbols
FVL; PCCF; THPH2; RPRGL1
NCBI Protein Information
coagulation factor V; factor V Leiden; proaccelerin, labile factor; activated protein c cofactor; coagulation factor V jinjiang A2 domain
UniProt Protein Name
Coagulation factor V
Protein Family
UniProt Gene Name
F5
UniProt Entry Name
FA5_HUMAN
Similar Products
Product Notes
The F5 f5 (Catalog #AAA126588) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The F5 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's F5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot (WB): 1:500-1:2000. Researchers should empirically determine the suitability of the F5 f5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "F5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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