Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using F2RL2 Polyclonal Antibody at dilution 1:30)
Rabbit anti-Human F2RL2 Polyclonal Antibody | anti-F2RL2 antibody
F2RL2 Polyclonal Antibody
Centrifuge before opening to ensure complete recovery of vial contents.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using F2RL2 Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using F2RL2 Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using F2RL2 Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using F2RL2 Polyclonal Antibody at dilution 1:30)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]
Uniprot Description
PAR3: a G-protein coupled receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Interacts with INSC/inscuteable and probably GPSM2. Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.
Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5q13
Cellular Component: integral to plasma membrane; apical plasma membrane; extracellular region; plasma membrane
Molecular Function: protein binding; phosphoinositide phospholipase C activity; thrombin receptor activity
Biological Process: platelet activation; metabolic process; response to wounding; blood coagulation
Research Articles on F2RL2
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Product Notes
The F2RL2 f2rl2 (Catalog #AAA2523405) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The F2RL2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's F2RL2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100 Centrifuge before opening to ensure complete recovery of vial contents. Researchers should empirically determine the suitability of the F2RL2 f2rl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "F2RL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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