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Western Blot (WB) (Western blot analysis F111B using RAW264.7 whole cell lysates)

Rabbit anti-Human F111B Polyclonal Antibody | anti-F111B antibody

F111B Antibody

Gene Names
FAM111B; CANP; POIKTMP
Reactivity
Human
Applications
Western Blot
Synonyms
F111B; Polyclonal Antibody; F111B Antibody; FAM111B; CANP; Protein FAM111B; anti-F111B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
F111B Antibody detects endogenous levels of total F111B
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
704
Applicable Applications for anti-F111B antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human F111B
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis F111B using RAW264.7 whole cell lysates)

Western Blot (WB) (Western blot analysis F111B using RAW264.7 whole cell lysates)
Product Categories/Family for anti-F111B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
81,201 Da
NCBI Official Full Name
protein FAM111B isoform b
NCBI Official Synonym Full Names
family with sequence similarity 111 member B
NCBI Official Symbol
FAM111B
NCBI Official Synonym Symbols
CANP; POIKTMP
NCBI Protein Information
protein FAM111B
UniProt Protein Name
Protein FAM111B
UniProt Gene Name
FAM111B
UniProt Synonym Gene Names
CANP
UniProt Entry Name
F111B_HUMAN

NCBI Description

This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014]

Uniprot Description

FAM111B: Belongs to the FAM111 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11q12.1

Molecular Function: protein binding

Disease: Poikiloderma, Hereditary Fibrosing, With Tendon Contractures, Myopathy, And Pulmonary Fibrosis

Research Articles on F111B

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Product Notes

The F111B fam111b (Catalog #AAA9418926) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The F111B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's F111B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the F111B fam111b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "F111B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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