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Immunohistochemistry (IHC) (Anti-EXOC7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Goat EXOC7 Polyclonal Antibody | anti-EXOC7 antibody

Goat Polyclonal to Human EXOC7

Gene Names
EXOC7; EX070; EXO70; EXOC1; 2-5-3p; Exo70p; YJL085W
Reactivity
Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat
Predicted Reactivity: Zebrafish (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
EXOC7; Polyclonal Antibody; Goat Polyclonal to Human EXOC7; Anti-EXOC7 Antibody (Internal) IHC-plus; 2-5-3p; Exo70p; EXO70; KIAA1067; YJL085W; EX070; Exocyst complex component 7; Human EXOC7; anti-EXOC7 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat
Predicted Reactivity: Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human EXOC7. This antibody is expected to recognise all five reported isoforms (NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1).
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
684
Applicable Applications for anti-EXOC7 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:16000), IHC-P (5 ug/ml), WB (1:16000, 0.5 - 1.5 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic peptide C-DNIKNDPDKEYN from an internal region of human EXOC7 (NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1).
Immunogen Type
Synthetic peptide
Immunogen
EXOC7 antibody was raised against synthetic peptide C-DNIKNDPDKEYN from an internal region of human EXOC7 (NP_001013861.1; NP_056034.2; NP_001138769.1; NP_001138771.1; NP_001138770.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Elephant, Panda, Horse, Pig, Opossum, Turkey, Chicken, Platypus (100%); Lizard, Salmon, Zebrafish (92%).
Antigen Modification
Internal
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-EXOC7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-EXOC7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Antibody (0.5 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Western Blot (WB) (Antibody (0.5 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
80,650 Da
NCBI Official Full Name
exocyst complex component 7 isoform 1
NCBI Official Synonym Full Names
exocyst complex component 7
NCBI Official Symbol
EXOC7
NCBI Official Synonym Symbols
EX070; EXO70; EXOC1; 2-5-3p; Exo70p; YJL085W
NCBI Protein Information
exocyst complex component 7; exocyst complex component Exo70
UniProt Protein Name
Exocyst complex component 7
Protein Family
UniProt Gene Name
EXOC7
UniProt Synonym Gene Names
EXO70; KIAA1067
UniProt Entry Name
EXOC7_HUMAN

NCBI Description

The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]

Uniprot Description

EXOC7: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. Belongs to the EXO70 family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 17q25.1

Cellular Component: membrane; plasma membrane; exocyst; microtubule organizing center; cytosol

Molecular Function: protein binding

Biological Process: protein transport; cellular protein metabolic process; exocytosis; organelle organization and biogenesis

Research Articles on EXOC7

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Product Notes

The EXOC7 exoc7 (Catalog #AAA241966) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human EXOC7 reacts with Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Pig, Rat Predicted Reactivity: Zebrafish (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's EXOC7 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:16000), IHC-P (5 ug/ml), WB (1:16000, 0.5 - 1.5 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the EXOC7 exoc7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXOC7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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