Rabbit anti-Human, Mouse EXOC3L Polyclonal Antibody | anti-EXOC3L antibody

EXOC3L, CT (EXOC3L1, EXOC3L, Exocyst complex component 3-like protein, Protein Jiangli) (Biotin)

Cat. Num. AAA6297088

• Gene Names: EXOC3L1; EXOC3L
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, ELISA, Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: EXOC3L; Polyclonal Antibody; CT (EXOC3L1; Exocyst complex component 3-like protein; Protein Jiangli) (Biotin); EXOC3L1; Protein Jiangli; anti-EXOC3L antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-EXOC3L antibody: Immunofluorescence (IF), ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IF: 1:10-50; ELISA: 1:1,000; IHC: 1:10-50; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: EXOC3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-688 amino acids from the C-terminal region of human EXOC3L.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(EXOC3L Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the EXOC3L antibody detected the EXOC3L protein (arrow).)

Western Blot (WB)

(EXOC3L Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the EXOC3L antibody detected the EXOC3L protein (arrow).)

Immunohistochemistry (IHC)

(EXOC3L Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EXOC3L Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis of EXOC3L Antibody (C-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)

Product Categories/Family for anti-EXOC3L antibody

Antibodies; Proteins

References

Saito, T., et al. Biomed. Res. 29(2):85-91(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 106879204
• NCBI GeneID: 283849
• NCBI Accession #: NP_848611.2
• NCBI GenBank Nucleotide #: NM_178516.3
• UniProt Accession #: Q86VI1; Q8NAD2; Q8TEN2; A8K7I9
• Molecular Weight: 81,678 Da
• NCBI Official Full Name: exocyst complex component 3-like protein
• NCBI Official Synonym Full Names: exocyst complex component 3-like 1
• NCBI Official Symbol: EXOC3L1
• NCBI Official Synonym Symbols: EXOC3L
• NCBI Protein Information: exocyst complex component 3-like protein; protein Jiangli
• UniProt Protein Name: Exocyst complex component 3-like protein
• UniProt Gene Name: EXOC3L1
• UniProt Synonym Gene Names: EXOC3L
• UniProt Entry Name: EX3L1_HUMAN

Uniprot Description

EXOC3L: As part of the exocyst, may play a role in regulated exocytosis of insulin granules. Belongs to the SEC6 family.

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: transport vesicle; exocyst; secretory granule

Molecular Function: SNARE binding

Biological Process: exocytosis; exocyst localization; peptide hormone secretion