Western Blot (WB)
(Host: RabbitTarget Name: ETFDSample Tissue: Human Fetal LiverAntibody Dilution: 1ug/ml)
Rabbit anti-Human ETFDH Polyclonal Antibody | anti-ETFDH antibody
ETFDH Antibody - N-terminal region
Western Blot (WB)
(Host: RabbitTarget Name: ETFDSample Tissue: Human Fetal LiverAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: ETFDSample Tissue: Human Fetal LiverAntibody Dilution: 1ug/ml)
Target Description: This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of the electron-transfer system in mitochondria and is essential for electron transfer from a number of mitochondrial flavin-containing dehydrogenases to the main respiratory chain. Mutations in this gene are associated with glutaric acidemia. Alternatively spliced transcript variants that encode distinct isoforms have been observed. [provided by RefSeq, Aug 2013]
Uniprot Description
ETFDH: Accepts electrons from ETF and reduces ubiquinone. Defects in ETFDH are the cause of glutaric aciduria type 2C (GA2C). GA2C is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Belongs to the ETF-QO/FixC family.
Protein type: Mitochondrial; EC 1.5.5.1; Membrane protein, integral; Oxidoreductase
Chromosomal Location of Human Ortholog: 4q32-q35
Cellular Component: mitochondrial matrix; mitochondrial membrane; integral to mitochondrial inner membrane
Molecular Function: ubiquinone binding; electron carrier activity; FAD binding; metal ion binding; oxidoreductase activity, oxidizing metal ions with flavin as acceptor; 4 iron, 4 sulfur cluster binding; oxidoreductase activity; quinone binding; electron-transferring-flavoprotein dehydrogenase activity
Biological Process: cellular metabolic process; response to oxidative stress; fatty acid beta-oxidation using acyl-CoA dehydrogenase
Disease: Multiple Acyl-coa Dehydrogenase Deficiency
Research Articles on ETFDH
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Product Notes
The ETFDH etfdh (Catalog #AAA3219719) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ETFDH Antibody - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ETFDH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ETFDH etfdh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: RITTHYTIYP RDKDKRWEGV NMERFAEEAD VVIVGAGPAG LSAAVRLKQL. It is sometimes possible for the material contained within the vial of "ETFDH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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