Rabbit anti-Human ESYT1 Polyclonal Antibody | anti-ESYT1 antibody

ESYT1, CT (ESYT1, FAM62A, KIAA0747, MBC2, Extended synaptotagmin-1, Membrane-bound C2 domain-containing protein) (MaxLight 750)

Cat. Num. AAA6296908

• Gene Names: ESYT1; MBC2; FAM62A
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ESYT1; Polyclonal Antibody; CT (ESYT1; FAM62A; KIAA0747; MBC2; Extended synaptotagmin-1; Membrane-bound C2 domain-containing protein) (MaxLight 750); Membrane-bound C2 domain-containing protein; anti-ESYT1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ESYT1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.

• Applicable Applications for anti-ESYT1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1002-1031 in the C-terminal region of human ESYT1, UniProt Accession #NP_056107.1; NP_001171725.1; Q9BSJ8.
• Conjugate: MaxLight750
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis in K562 cell line lysates (35ug/lane) using. This demonstrates MBS646330 detected the ESYT1 protein (arrow).)

Related Product Information for anti-ESYT1 antibody

ESYT1 may play a role as calcium-regulated intrinsic membrane protein (By similarity).

Product Categories/Family for anti-ESYT1 antibody

Antibodies; Syntaxin; Synaptotagmin; Synaptophysin

References

Craxton, M. BMC Genomics 8, 259 (2007): Laveder, P., et al. Nucleic Acids Res. 30 (9), E38 (2002): Morris, N.J., et al. Biochim. Biophys. Acta 1431(2):525-530(1999).

NCBI and Uniprot Product Information

• NCBI GI #: 14149680
• NCBI GeneID: 23344
• NCBI Accession #: NP_056107.1; NP_001171725.1
• NCBI GenBank Nucleotide #: NM_015292.2
• UniProt Accession #: Q9BSJ8; O94848; Q6PJN4; Q9H6J1; Q9H6W2; Q9Y416; A0FGR7; A8K2S2
• Molecular Weight: 124,003 Da
• NCBI Official Full Name: extended synaptotagmin-1 isoform 2
• NCBI Official Synonym Full Names: extended synaptotagmin-like protein 1
• NCBI Official Symbol: ESYT1
• NCBI Official Synonym Symbols: MBC2; FAM62A
• NCBI Protein Information: extended synaptotagmin-1; membrane-bound C2 domain-containing protein; family with sequence similarity 62 (C2 domain containing), member A
• UniProt Protein Name: Extended synaptotagmin-1
• Protein Family: Extended synaptotagmin
• UniProt Gene Name: ESYT1
• UniProt Synonym Gene Names: FAM62A; KIAA0747; MBC2; E-Syt1
• UniProt Entry Name: ESYT1_HUMAN

Uniprot Description

ESYT1: May play a role as calcium-regulated intrinsic membrane protein. Belongs to the extended synaptotagmin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: membrane; plasma membrane; integral to endoplasmic reticulum membrane

Molecular Function: protein binding; metal ion binding; phospholipid binding

Biological Process: lipid transport