Rabbit anti-Human ERMIN Polyclonal Antibody | anti-ERMIN antibody

ERMIN, ID (ERMN, KIAA1189, Ermin, Juxtanodin) (AP)

Cat. Num. AAA6296580

• Gene Names: ERMN; JN; KIAA1189
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ERMIN; Polyclonal Antibody; ID (ERMN; KIAA1189; Ermin; Juxtanodin) (AP); ERMN; Juxtanodin; anti-ERMIN antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-ERMIN antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ERMIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 120-150 from the Central region of human ERMIN.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ERMIN Antibody (Center) western blot analysis in Jurkat,293 cell line lysates (35ug/lane).This demonstrates the ERMIN antibody detected the ERMIN protein (arrow).)

Flow Cytometry (FC/FACS)

(ERMIN Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-ERMIN antibody

ERMIN plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. ERMIN may play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

Product Categories/Family for anti-ERMIN antibody

Antibodies; KIAA; orf

References

Brockschnieder, D., et al. J. Neurosci. 26(3):757-762(2006). Zhang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 102(32):11527-11532(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 58331177
• NCBI GeneID: 57471
• NCBI Accession #: NP_001009959.1
• NCBI GenBank Nucleotide #: NM_001009959.2
• UniProt Accession #: Q8TAM6; Q9ULN1; B4DKA6
• Molecular Weight: 34,301 Da
• NCBI Official Full Name: ermin isoform a
• NCBI Official Synonym Full Names: ermin
• NCBI Official Symbol: ERMN
• NCBI Official Synonym Symbols: JN; KIAA1189
• NCBI Protein Information: ermin
• UniProt Protein Name: Ermin
• Protein Family: Ermin
• UniProt Gene Name: ERMN
• UniProt Synonym Gene Names: KIAA1189; JN

Uniprot Description

Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS ().