Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ERH Polyclonal Antibody at dilution of 1:55(×200))
Rabbit anti-Human, Mouse ERH Polyclonal Antibody | anti-ERH antibody
ERH Polyclonal Antibody
Gene Names
ERH; DROER
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
ERH; Polyclonal Antibody; ERH Polyclonal Antibody; DROER; Enhancer of rudimentary homolog (Drosophila); Enhancer of rudimentary homolog; FLJ27340; HGNC:3447; anti-ERH antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.96mg/mL (varies by lot)
Sequence Length
104
Applicable Applications for anti-ERH antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:40-1:200
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human ERH
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ERH Polyclonal Antibody at dilution of 1:55(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ERH Polyclonal Antibody at dilution of 1:55(×200))
Related Product Information for anti-ERH antibody
ERH (enhancer of rudimentary homolog), also known as DROER, is a 104 amino acid transcriptional coregulator that is ubiquitously expressed and highly conserved among eukaryotes. ERH may play a role in cell cycle regulation and pyrimidine biosynthesis. ERH represses the function of the coactivator PCBD, preventing it from enhancing the activity of the tissue-specific transcription factor HNF-1 (hepatocyte nuclear factor-1). HNF-1 is a homeodomain transcription factor that binds DNA as a dimer and the HNF-1/DNA complex is stabilized by PCBD. By repressing PCBD, ERH disrupts the stability of the HNF-1/DNA complex, affecting the expression of multiple genes in the liver. The structure of ERH is characterized by a single domain consisting of three alpha-helices and four beta-strands. ERH has a long flexible loop that is significantly conserved, suggesting that this loop region may be important for the function of ERH. ERH has two casein kinase II phosphorylation sites that are thought to disrupt the ability of ERH to dimerize.
Product Categories/Family for anti-ERH antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
enhancer of rudimentary homolog
NCBI Official Synonym Full Names
ERH mRNA splicing and mitosis factor
NCBI Official Symbol
ERH
NCBI Official Synonym Symbols
DROER
NCBI Protein Information
enhancer of rudimentary homolog
UniProt Protein Name
Enhancer of rudimentary homolog
Protein Family
UniProt Gene Name
ERH
UniProt Entry Name
ERH_HUMAN
Uniprot Description
ERH: May have a role in the cell cycle. Belongs to the E(R) family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 14q24.1
Cellular Component: membrane; midbody
Biological Process: osteoblast differentiation; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; cell cycle; pyrimidine nucleoside metabolic process
Research Articles on ERH
Similar Products
Product Notes
The ERH erh (Catalog #AAA2562918) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ERH Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ERH can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:40-1:200 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the ERH erh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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