Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Her3/ErbB3 antibody (left) or the same antibody preincubated with with blocking peptide (right))
Rabbit ERBB3 Polyclonal Antibody | anti-ERBB3 antibody
ERBB3 antibody
Gene Names
erbb3b; erbb3
Applications
Immunohistochemistry, Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
ERBB3; Polyclonal Antibody; ERBB3 antibody; Rabbit polyclonal ERBB3 antibody; Polyclonal ERBB3 antibody; Anti-ERBB3 antibody; Receptor tyrosine-protein kinase erbB-3 antibody; ERBB-3; Her3 antibody; ERBB-3 antibody; ERBB 3; LCCS2 antibody; ERBB 3 antibody; anti-ERBB3 antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Liquid form in PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl,0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1429
Applicable Applications for anti-ERBB3 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC: 1:50-1:100
WB: 1:500-1:1000
WB: 1:500-1:1000
Immunogen
ERBB3 antibody was raised in Rabbit using the peptide sequence around aa 1326~1330 (P-D-Y-W-H) derived from Human Her3/ErbB3 as the immunogen.
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Aliquot and store at-20 degree C for long term storage.
Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Her3/ErbB3 antibody (left) or the same antibody preincubated with with blocking peptide (right))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Her3/ErbB3 antibody (left) or the same antibody preincubated with with blocking peptide (right))
Western Blot (WB)
(Western Blot analysis of extracts from A431 cells using Her3/ErbB3 antibody)
Western Blot (WB)
(Western Blot analysis of extracts from A431 cells using Her3/ErbB3 antibody)
Related Product Information for anti-ERBB3 antibody
ERBB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors.
Product Categories/Family for anti-ERBB3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
158,993 Da
NCBI Official Full Name
Erbb3
NCBI Official Synonym Full Names
erb-b2 receptor tyrosine kinase 3b
NCBI Official Symbol
erbb3b
NCBI Official Synonym Symbols
erbb3
NCBI Protein Information
erbB-3b
UniProt Protein Name
Erbb3
Protein Family
UniProt Gene Name
erbb3b
Research Articles on ERBB3
Similar Products
Product Notes
The ERBB3 erbb3b (Catalog #AAA5309836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ERBB3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:50-1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the ERBB3 erbb3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERBB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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