Goat Epstein Barr Virus, Nuclear Antigen Polyclonal Antibody
Epstein Barr Virus, Nuclear Antigen (EBV)
Applications
ELISA, Immunofluorescence
Purity
Highly PurifiedPurified by Ion Exchange chromatography.
Synonyms
Epstein Barr Virus; Nuclear Antigen; Polyclonal Antibody; Nuclear Antigen (EBV); Anti -Epstein Barr Virus; anti-Epstein Barr Virus; Nuclear Antigen antibody
Host
Goat
Clonality
Polyclonal
Specificity
Recognizes Epstein-Barr nuclear antigen. Non-reactive with human lymphoid cells. Functions in ELISA against various recombinant EBNA-1 preps.
Purity/Purification
Highly Purified
Purified by Ion Exchange chromatography.
Purified by Ion Exchange chromatography.
Form/Format
Supplied as a liquid in 0.01M PBS, pH 7.2, 0.1% sodium azide.
Applicable Applications for anti-Epstein Barr Virus, Nuclear Antigen antibody
ELISA (EL/EIA), Immunofluorescence (IF)
Application Notes
Suitable for use in ELISA and IFA., , Recommended Dilution:, Optimal dilutions to be determined by the researcher.
Immunogen
Purified recombinant EBNA-1.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Epstein Barr Virus, Nuclear Antigen antibody
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
Product Categories/Family for anti-Epstein Barr Virus, Nuclear Antigen antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
Epstein-Barr nuclear antigen 6
Uniprot Description
Plays an essential role for the activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA6 probably contributes to a negative autoregulatory control loop. Alternatively, EBNA6 also regulates the transcription of the EBV oncogene LMP1 in a cell cycle-dependent manner. Modulates the activity of several host proteins involved in cell cycle regulation including host cyclin A, MYC, RB, p21 and p27 mainly through binding to the host SCF(SKP2) complex. Inhibits the promoter of host H2AX and targets H2AX to proteasomal degradation in order to promote latency and cell proliferation.
Similar Products
Product Notes
The Epstein Barr Virus, Nuclear Antigen (Catalog #AAA624641) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Epstein Barr Virus, Nuclear Antigen can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunofluorescence (IF). Suitable for use in ELISA and IFA.,, Recommended Dilution:, Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Epstein Barr Virus, Nuclear Antigen for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Epstein Barr Virus, Nuclear Antigen, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
