Western Blot (WB)
(EPS8L2 Antibody (N-term) western blot analysis in A431 cell line lysates (35ug/lane).This demonstrates the EPS8L2 antibody detected the EPS8L2 protein (arrow).)
Rabbit anti-Human EPS8L2 Polyclonal Antibody | anti-EPS8L2 antibody
EPS8L2, NT (EPS8L2, EPS8R2, Epidermal growth factor receptor kinase substrate 8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2) (APC)
Gene Names
EPS8L2; EPS8R2
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
EPS8L2; Polyclonal Antibody; NT (EPS8L2; EPS8R2; Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2) (APC); Epidermal growth factor receptor pathway substrate 8-related protein 2; anti-EPS8L2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-EPS8L2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
EPS8L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the N-terminal region of human EPS8L2.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(EPS8L2 Antibody (N-term) western blot analysis in A431 cell line lysates (35ug/lane).This demonstrates the EPS8L2 antibody detected the EPS8L2 protein (arrow).)
Western Blot (WB)
(EPS8L2 Antibody (N-term) western blot analysis in A431 cell line lysates (35ug/lane).This demonstrates the EPS8L2 antibody detected the EPS8L2 protein (arrow).)
Related Product Information for anti-EPS8L2 antibody
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling.
Product Categories/Family for anti-EPS8L2 antibody
References
Kim, J.E., et al. J. Proteome Res. 4(4):1339-1346(2005). Offenhauser, N., et al. Mol. Biol. Cell 15(1):91-98(2004). Tocchetti, A., et al. Genomics 81(2):234-244(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80,621 Da
NCBI Official Full Name
epidermal growth factor receptor kinase substrate 8-like protein 2
NCBI Official Synonym Full Names
EPS8-like 2
NCBI Official Symbol
EPS8L2
NCBI Official Synonym Symbols
EPS8R2
NCBI Protein Information
epidermal growth factor receptor kinase substrate 8-like protein 2; EPS8-like protein 2; EPS8-related protein 2; epidermal growth factor receptor pathway substrate 8-related protein 2
UniProt Protein Name
Epidermal growth factor receptor kinase substrate 8-like protein 2
UniProt Gene Name
EPS8L2
UniProt Synonym Gene Names
EPS8R2; EPS8-like protein 2
UniProt Entry Name
ES8L2_HUMAN
NCBI Description
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]
Uniprot Description
EPS8L2: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rac/Rho; Actin-binding
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: protein complex; cytoplasm; plasma membrane; vesicle
Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; actin binding
Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction
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Product Notes
The EPS8L2 eps8l2 (Catalog #AAA6296119) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPS8L2, NT (EPS8L2, EPS8R2, Epidermal growth factor receptor kinase substrate 8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EPS8L2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the EPS8L2 eps8l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPS8L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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