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Western Blot (WB) (Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody. )

Rabbit anti-Human, Mouse EPS8L2 Polyclonal Antibody | anti-EPS8L2 antibody

EPS8L2 Antibody

Gene Names
EPS8L2; EPS8R2
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
EPS8L2; Polyclonal Antibody; EPS8L2 Antibody; Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8-like protein 2; EPS8R2; anti-EPS8L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Applicable Applications for anti-EPS8L2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:3000
Immunogen
Synthesized peptide derived from internal of human ES8L2.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody. )

Western Blot (WB) (Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody. )
Product Categories/Family for anti-EPS8L2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
80,621 Da
NCBI Official Full Name
epidermal growth factor receptor kinase substrate 8-like protein 2
NCBI Official Synonym Full Names
EPS8-like 2
NCBI Official Symbol
EPS8L2
NCBI Official Synonym Symbols
EPS8R2
NCBI Protein Information
epidermal growth factor receptor kinase substrate 8-like protein 2; EPS8-like protein 2; EPS8-related protein 2; epidermal growth factor receptor pathway substrate 8-related protein 2
UniProt Protein Name
Epidermal growth factor receptor kinase substrate 8-like protein 2
UniProt Gene Name
EPS8L2
UniProt Synonym Gene Names
EPS8R2; EPS8-like protein 2
UniProt Entry Name
ES8L2_HUMAN

NCBI Description

This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]

Uniprot Description

EPS8L2: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rac/Rho; Actin-binding

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: protein complex; cytoplasm; plasma membrane; vesicle

Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; actin binding

Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction

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Product Notes

The EPS8L2 eps8l2 (Catalog #AAA7130971) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPS8L2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EPS8L2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:3000. Researchers should empirically determine the suitability of the EPS8L2 eps8l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPS8L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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