Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using EPHX1 antibody.)
Rabbit EPHX1 Polyclonal Antibody | anti-EPHX1 antibody
EPHX1 Antibody
Immunohistochemistry: 1:50 - 1:100
Immunofluorescence: 1:20 - 1:100
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using EPHX1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using EPHX1 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human esophageal cancer using EPHX1 antibody at dilution of 1:100 (400x lens).)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human esophageal cancer using EPHX1 antibody at dilution of 1:100 (400x lens).)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human esophageal cancer using EPHX1 antibody at dilution of 1:100 (200x lens).)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human esophageal cancer using EPHX1 antibody at dilution of 1:100 (200x lens).)
NCBI and Uniprot Product Information
NCBI Description
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008]
Uniprot Description
Ephx1: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls. Defects in EPHX1 are a cause of familial hypercholanemia (FHCA). FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption. Belongs to the peptidase S33 family.
Protein type: Hydrolase; Membrane protein, integral; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 3.3.2.9
Chromosomal Location of Human Ortholog: 1q42.1
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: cis-stilbene-oxide hydrolase activity; epoxide hydrolase activity
Biological Process: response to toxin; aromatic compound catabolic process; response to organic cyclic substance
Disease: Hypercholanemia, Familial; Preeclampsia/eclampsia 1
Research Articles on EPHX1
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Product Notes
The EPHX1 ephx1 (Catalog #AAA9411707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPHX1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EPHX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Western blotting: 1:500 - 1:2000 Immunohistochemistry: 1:50 - 1:100 Immunofluorescence: 1:20 - 1:100. Researchers should empirically determine the suitability of the EPHX1 ephx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPHX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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