Western Blot (WB)
(Western blot analysis of lysates from Hela. SH-SY5Y, mouse NIH/3T3 cell line (from left to right), using Ephb3 Antibody (Center). MBS9203552 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit anti-Human, mouse Ephb3 Polyclonal Antibody | anti-Ephb3 antibody
Mouse Ephb3 Antibody (Center)
Western Blot (WB)
(Western blot analysis of lysates from Hela. SH-SY5Y, mouse NIH/3T3 cell line (from left to right), using Ephb3 Antibody (Center). MBS9203552 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from Hela. SH-SY5Y, mouse NIH/3T3 cell line (from left to right), using Ephb3 Antibody (Center). MBS9203552 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
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Adams R.H.,et al.Genes Dev. 13:295-306(1999).
Imondi R.,et al.Development 127:1397-1410(2000).
NCBI and Uniprot Product Information
Uniprot Description
EphB3: a ubiquitous receptor tyrosine kinase of the Eph family. A receptor for ephrin-B family members: ephrin-B1 and -B2. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease. EphA receptors bind to GPI-anchored ephrin-A ligands, while EphB receptors bind to ephrin-B proteins that have a transmembrane and cytoplasmic domain. Interactions between EphB receptor kinases and ephrin-B proteins transduce signals bidirectionally, signaling to both interacting cell types. Eph receptors and ephrins also regulate the adhesion of endothelial cells and are required for the remodeling of blood vessels.EphB3 contains 1 sterile alpha motif (SAM) domain and 2 fibronectin type III domains.
Protein type: Protein kinase, TK; Kinase, protein; EC 2.7.10.1; Membrane protein, integral; Protein kinase, tyrosine (receptor); TK group; Eph family
Cellular Component: cell projection; membrane; integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: transferase activity; transmembrane-ephrin receptor activity; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; ephrin receptor activity; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; kinase activity; axon guidance receptor activity; ATP binding; protein kinase activity
Biological Process: nervous system development; axon guidance; cell migration; peptidyl-tyrosine phosphorylation; thymus development; multicellular organismal development; protein amino acid autophosphorylation; axonal fasciculation; central nervous system projection neuron axonogenesis; digestive tract morphogenesis; palate development; regulation of axonogenesis; signal transduction; protein amino acid phosphorylation; corpus callosum development; positive regulation of synaptogenesis; regulation of cell-cell adhesion; ephrin receptor signaling pathway; angiogenesis; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; urogenital system development; retinal ganglion cell axon guidance
Research Articles on Ephb3
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Product Notes
The Ephb3 ephb3 (Catalog #AAA9203552) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mouse Ephb3 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Ephb3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:500-1:1000. Researchers should empirically determine the suitability of the Ephb3 ephb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ephb3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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