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Western Blot (WB) (Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 μg/mL and (B) 2 μg/mL.)

Rabbit EphA10 Polyclonal Antibody | anti-EPHA10 antibody

EphA10 Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
EphA10 Antibody is affinity chromatography purified via peptide column.
Synonyms
EphA10; Polyclonal Antibody; EphA10 Antibody; Ephrin type-A receptor 10; EPH receptor A10; anti-EPHA10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
EphA10 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1008
Applicable Applications for anti-EPHA10 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
EphA10 antibody can be used for detection of EphA10 by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
EphA10 antibody was raised against a 14 amino acid synthetic peptide of near the amino terminus of human EphA10.
Buffer
EphA10 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
EphA10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 μg/mL and (B) 2 μg/mL.)

Western Blot (WB) (Western blot analysis of EphA10 in 293 cell lysate with EphA10 antibody at (A) 1 μg/mL and (B) 2 μg/mL.)
Related Product Information for anti-EPHA10 antibody
EphA10 Antibody: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,293 Da
NCBI Official Full Name
ephrin type-A receptor 10 isoform 3
NCBI Official Synonym Full Names
EPH receptor A10
NCBI Official Symbol
EPHA10
NCBI Protein Information
ephrin type-A receptor 10; EphA10s protein
UniProt Protein Name
Ephrin type-A receptor 10
Protein Family
UniProt Gene Name
EPHA10
UniProt Entry Name
EPHAA_HUMAN

NCBI Description

Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008]

Uniprot Description

EphA10: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Protein kinase, tyrosine (receptor); Kinase, protein; Protein kinase, TK; EC 2.7.10.1; TK group; Eph family

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: protein binding; transmembrane-ephrin receptor activity; ephrin receptor activity; ATP binding

Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; ephrin receptor signaling pathway

Research Articles on EPHA10

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Product Notes

The EPHA10 epha10 (Catalog #AAA151050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EphA10 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EphA10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). EphA10 antibody can be used for detection of EphA10 by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the EPHA10 epha10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EphA10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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