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Rabbit anti-Human ENY2 Polyclonal Antibody | anti-ENY2 antibody

ENY2 Antibody, HRP conjugated

Gene Names
ENY2; DC6; e(y)2
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
ENY2; Polyclonal Antibody; ENY2 Antibody; HRP conjugated; Transcription and mRNA export factor ENY2UniRule annotation; Enhancer of yellow 2 transcription factor homolog; anti-ENY2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
96
Applicable Applications for anti-ENY2 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human Transcription and mRNA export factor ENY2 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-87712 / sc-87713
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-ENY2 antibody
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,984 Da
NCBI Official Full Name
transcription and mRNA export factor ENY2 isoform 2
NCBI Official Synonym Full Names
enhancer of yellow 2 homolog (Drosophila)
NCBI Official Symbol
ENY2
NCBI Official Synonym Symbols
DC6; e(y)2
NCBI Protein Information
transcription and mRNA export factor ENY2
UniProt Protein Name
Transcription and mRNA export factor ENY2
UniProt Gene Name
ENY2
UniProt Entry Name
ENY2_HUMAN

Uniprot Description

ENY2: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Belongs to the ENY2 family.

Protein type: Ubiquitin conjugating system; Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 8q23.1

Cellular Component: nuclear pore

Molecular Function: chromatin binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription coactivator activity

Biological Process: establishment and/or maintenance of chromatin architecture; histone deubiquitination; poly(A)+ mRNA export from nucleus; positive regulation of transcription, DNA-dependent; protein transport; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter

Research Articles on ENY2

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Product Notes

The ENY2 eny2 (Catalog #AAA1497485) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ENY2 Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ENY2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ENY2 eny2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENY2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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