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Western Blot (WB) (Western blot analysis of extracts from Jurkat cells using EMR3 antibody)

Rabbit EMR3 Polyclonal Antibody | anti-EMR3 antibody

EMR3 antibody

Gene Names
ADGRE3; EMR3
Applications
Western Blot, ELISA
Synonyms
EMR3; Polyclonal Antibody; EMR3 antibody; Polyclonal EMR3; Anti-EMR3; EGF-Like Module-Containing Mucin-Like Receptor 3; EMR 3; EMR -3; anti-EMR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
EMR3 antibody detects endogenous levels of total EMR3 protein
Form/Format
Purified IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
600
Applicable Applications for anti-EMR3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:10000
Biological Significance
EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system.
Immunogen
EMR3 antibody was raised in Rabbit using a synthesized peptide derived from C-terminal of human EMR3 as the immunogen
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeated freeze-thaw cycles

Western Blot (WB)

(Western blot analysis of extracts from Jurkat cells using EMR3 antibody)

Western Blot (WB) (Western blot analysis of extracts from Jurkat cells using EMR3 antibody)
Related Product Information for anti-EMR3 antibody
Rabbit polyclonal EMR3 antibody
Product Categories/Family for anti-EMR3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
12,703 Da
NCBI Official Full Name
EMR3
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor E3
NCBI Official Symbol
ADGRE3
NCBI Official Synonym Symbols
EMR3
NCBI Protein Information
adhesion G protein-coupled receptor E3
UniProt Protein Name
Adhesion G protein-coupled receptor E3
UniProt Gene Name
ADGRE3
UniProt Entry Name
AGRE3_HUMAN

NCBI Description

This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]

Uniprot Description

EMR3: Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: extracellular space; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on EMR3

Similar Products

Product Notes

The EMR3 adgre3 (Catalog #AAA5303509) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's EMR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the EMR3 adgre3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EMR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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