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Western Blot (WB) (ELP3 rabbit polyclonal antibody. Western Blot analysis of ELP3 expression in A-431.)

Rabbit anti-Human ELP3 Polyclonal Antibody | anti-ELP3 antibody

ELP3 (Elongator Complex Protein 3, hELP3, FLJ10422) (AP)

Gene Names
ELP3; KAT9
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ELP3; Polyclonal Antibody; ELP3 (Elongator Complex Protein 3; hELP3; FLJ10422) (AP); anti-ELP3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ELP3.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-ELP3 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human ELP3, aa1-547 (NP_060561.3).
Immunogen Sequence
MRQKRKGDLSPAELMMLTIGDVIKQLIEAHEQGKDIDLNKVKTKTAAKYGLSAQPRLVDIIAAVPPQYRKVLMPKLKAKPIRTASGIAVVAVMCKPHRCPHISFTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPFLQTRHRIEQLKQLGHSVDKVEFIVMGGTFMALPEEYRDYFIRNLHDALSGHTSNNIYEAVKYSERSLTKCIGITIETRPDYCMKRHLSDMLTYGCTRLEIGVQSVYEDVARDTNRGHTVKAVCESFHLAKDSGFKVVAHMMPDLPNVGLERDIEQFTEFFENPAFRPDGLKLYPTLVIRGTGLYELWKSGRYKSYSPSDLVELVARILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGIQCRDVRTREVGIQEIHHKVRPYQVELVRRDYVANGGWETFLSYEDPDQDILIGLLRLRKCSEETFRFELGGGVSIVRELHVYGSVVPVSSRDPTKFQHQGFGMLLMEEAERIAREEHGSGKIAVISGVGTRNYYRKIGYRLQGPYMVKMLK
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ELP3 rabbit polyclonal antibody. Western Blot analysis of ELP3 expression in A-431.)

Western Blot (WB) (ELP3 rabbit polyclonal antibody. Western Blot analysis of ELP3 expression in A-431.)

Western Blot (WB)

(Western Blot analysis of ELP3 expression in transfected 293T cell line by ELP3 polyclonal antibody. Lane 1: ELP3 transfected lysate (62.3kD). Lane 2: Non-transfected lysate. )

Western Blot (WB) (Western Blot analysis of ELP3 expression in transfected 293T cell line by ELP3 polyclonal antibody. Lane 1: ELP3 transfected lysate (62.3kD). Lane 2: Non-transfected lysate. )
Related Product Information for anti-ELP3 antibody
Elongator complex protein 3 (ELP3) is a catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. It may also have a methyltransferase activity.
Product Categories/Family for anti-ELP3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,202 Da
NCBI Official Full Name
elongator complex protein 3 isoform 1
NCBI Official Synonym Full Names
elongator acetyltransferase complex subunit 3
NCBI Official Symbol
ELP3
NCBI Official Synonym Symbols
KAT9
NCBI Protein Information
elongator complex protein 3; elongation protein 3 homolog
UniProt Protein Name
Elongator complex protein 3
Protein Family
UniProt Gene Name
ELP3
UniProt Synonym Gene Names
hELP3
UniProt Entry Name
ELP3_HUMAN

NCBI Description

ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Uniprot Description

ELP3: a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II.

Protein type: EC 2.3.1.48; Acetyltransferase

Chromosomal Location of Human Ortholog: 8p21.1

Cellular Component: transcription elongation factor complex; Elongator holoenzyme complex; cytoplasm; nucleolus; histone acetyltransferase complex

Molecular Function: protein binding; H4 histone acetyltransferase activity; metal ion binding; iron-sulfur cluster binding; phosphorylase kinase regulator activity; H3 histone acetyltransferase activity

Biological Process: tRNA wobble uridine modification; regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; central nervous system development; RNA elongation from RNA polymerase II promoter; neuron migration; regulation of protein kinase activity; positive regulation of cell migration

Research Articles on ELP3

Similar Products

Product Notes

The ELP3 elp3 (Catalog #AAA6377294) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ELP3 (Elongator Complex Protein 3, hELP3, FLJ10422) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ELP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ELP3 elp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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