Rabbit anti-Mouse, Rat Elovl4 Polyclonal Antibody | anti-Elovl4 antibody

Anti-Elovl4 Antibody

Cat. Num. AAA1753622

• Reactivity: Mouse, Rat
• Applications: Western Blot, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
• Purity: Immunogen affinity purified.
• Synonyms: Elovl4; Polyclonal Antibody; Anti-Elovl4 Antibody; Elongation of very long chain fatty acids protein 4; EC 2. 3. 1. 199; 3-keto acyl-CoA synthase Elovl4; ELOVL fatty acid elongase 4; ELOVL FA elongase 4; Very long chain 3-ketoacyl-CoA synthase 4; Very long chain 3-oxoacyl-CoA synthase 4; elongation of very long chain fatty acids (FEN1/Elo2; SUR4/Elo3; yeast)-like 4; anti-Elovl4 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Rabbit IgG polyclonal antibody for Elovl4 detection.
• Purity/Purification: Immunogen affinity purified.
• Form/Format: Lyophilized. Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

• Applicable Applications for anti-Elovl4 antibody: Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS/FCM), Direct ELISA (EIA)
• Application Notes: WB: 0.25-0.5ug/ml|Mouse, Rat|; ICC/IF: 5ug/ml|Mouse|; FC/FACS/FCM: 1-3ug/1x106 cells|Mouse|; Direct ELISA: 0.1-0.5ug/ml|Mouse|
• Immunogen: E Coli-derived mouse Elovl4 recombinant protein (Position: M1-E312).
• Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
• Recommended Detection Systems: Recommended Detection Systems
• Preparation and Storage: Store at -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

Related Product Information for anti-Elovl4 antibody

Elongation of very long chain fatty acids protein 4 is a protein that in humans is encoded by the ELOVL4 gene. This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.

References

1. Agbaga, M. -P., Brush, R. S., Mandal, M. N. A., Henry, K., Elliott, M. H., Anderson, R. E. Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids. Proc. Nat. Acad. Sci. 105: 12843-12848, 2008.
2. Aldahmesh, M. A., Mohamed, J. Y., Alkuraya, H. S., Verma, I. C., Puri, R. D., Alaiya, A. A., Rizzo, W. B., Alkuraya, F. S. Recessive mutations in ELOVL4 cause ichthyosis, intellectual disability, and spastic quadriplegia. Am. J. Hum. Genet. 89: 745-750, 2011.
3. Alkuraya, H. S. Personal Communication. Riyaldh, Saudi Arabia 1/30/2012.

NCBI and Uniprot Product Information

• NCBI GI #: 225543343
• NCBI GeneID: 83603
• NCBI Accession #: NP_683743.2
• NCBI GenBank Nucleotide #: NM_148941.2
• UniProt Accession #: Q9EQC4; Q8JZV3
• Molecular Weight: 36,506 Da
• NCBI Official Full Name: elongation of very long chain fatty acids protein 4
• NCBI Official Synonym Full Names: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
• NCBI Official Symbol: Elovl4
• NCBI Protein Information: elongation of very long chain fatty acids protein 4; ELOVL FA elongase 4; ELOVL fatty acid elongase 4; 3-keto acyl-CoA synthase Elovl4; very-long-chain 3-oxoacyl-CoA synthase 4
• UniProt Protein Name: Elongation of very long chain fatty acids protein 4
• Protein Family: Elongation of very long chain fatty acids protein
• UniProt Gene Name: Elovl4
• UniProt Synonym Gene Names: ELOVL FA elongase 4
• UniProt Entry Name: ELOV4_MOUSE