Rabbit anti-Human, Mouse ELOVL4 Polyclonal Antibody | anti-ELOVL4 antibody

ELOVL4 Antibody

Cat. Num. AAA9506344

• Gene Names: ELOVL4; ADMD; CT118; ISQMR; SCA34; STGD2; STGD3
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Synonyms: ELOVL4; Polyclonal Antibody; ELOVL4 Antibody; Elongation of very long chain fatty acids protein 4; anti-ELOVL4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: ELOVL4 Antibody detects endogenous levels of total ELOVL4 protein.
• Purity/Purification: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 314

• Applicable Applications for anti-ELOVL4 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:40000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from human ELOVL4.
• Immunogen Range: 41-90
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from HeLa cells, using ELOVL4 Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 12232379
• NCBI GeneID: 6785
• NCBI Accession #: NP_073563.1
• NCBI GenBank Nucleotide #: NM_022726.3
• UniProt Accession #: Q9GZR5; Q5TCS2; Q86YJ1; Q9H139; B2R6B5
• Molecular Weight: 36 kDa
• NCBI Official Full Name: elongation of very long chain fatty acids protein 4
• NCBI Official Synonym Full Names: ELOVL fatty acid elongase 4
• NCBI Official Symbol: ELOVL4
• NCBI Official Synonym Symbols: ADMD; CT118; ISQMR; SCA34; STGD2; STGD3
• NCBI Protein Information: elongation of very long chain fatty acids protein 4
• UniProt Protein Name: Elongation of very long chain fatty acids protein 4
• Protein Family: Elongation of very long chain fatty acids protein
• UniProt Gene Name: ELOVL4
• UniProt Synonym Gene Names: ELOVL FA elongase 4

NCBI Description

This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration. [provided by RefSeq, Jul 2008]

Uniprot Description

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.