Rabbit anti-Human ELAVL4 Polyclonal Antibody | anti-ELAVL4 antibody

ELAVL4 (ELAV-like Protein 4, Hu-antigen D, HuD, Paraneoplastic Encephalomyelitis Antigen HuD, HUD, PNEM)

Cat. Num. AAA6000217

• Gene Names: ELAVL4; HUD; PNEM
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: ELAVL4; Polyclonal Antibody; ELAVL4 (ELAV-like Protein 4; Hu-antigen D; HuD; Paraneoplastic Encephalomyelitis Antigen HuD; HUD; PNEM); Anti -ELAVL4 (ELAV-like Protein 4; anti-ELAVL4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ELAVL4.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVGQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAITSLNGYRLGDRVLQVSFKTNKAHKS

• Applicable Applications for anti-ELAVL4 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human ELAVL4, aa1-366 (AAH36071.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of ELAVL4 expression in transfected 293T cell line by ELAVL4 polyclonal antibody. Lane 1: ELAVL4 transfected lysate (40.4kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ELAVL4 antibody

May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR. Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA.

Product Categories/Family for anti-ELAVL4 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 221316773
• NCBI GeneID: 1996
• NCBI Accession #: NP_001138249.1
• NCBI GenBank Nucleotide #: NM_001144777.1
• UniProt Accession #: P26378; Q8IYD4; Q96J74; Q96J75; Q9UD24; B1APY6; B1APY7; B7Z4G7
• Molecular Weight: 41,770 Da
• NCBI Official Full Name: ELAV-like protein 4 isoform 5
• NCBI Official Synonym Full Names: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4
• NCBI Official Symbol: ELAVL4
• NCBI Official Synonym Symbols: HUD; PNEM
• NCBI Protein Information: ELAV-like protein 4; Hu antigen D; hu-antigen D; paraneoplastic encephalomyelitis antigen HuD; Embryonic lethal, abnormal vision, Drosophila, homolog of, like-4; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
• UniProt Protein Name: ELAV-like protein 4
• Protein Family: ELAV-like protein
• UniProt Gene Name: ELAVL4
• UniProt Synonym Gene Names: HUD; PNEM; HuD
• UniProt Entry Name: ELAV4_HUMAN

Uniprot Description

ELAVL4: May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR. Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA. Belongs to the RRM elav family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 1p34

Molecular Function: mRNA 3'-UTR binding; RNA binding; nucleotide binding; AU-rich element binding

Biological Process: RNA processing; mRNA processing