Western Blot (WB)
(EIF4ENIF1 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the EIF4ENIF1 antibody detected the EIF4ENIF1 protein (arrow).)
Rabbit anti-Human EIF4ENIF1 Polyclonal Antibody | anti-EIF4ENIF1 antibody
EIF4ENIF1 Antibody (N-term)
Western Blot (WB)
(EIF4ENIF1 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the EIF4ENIF1 antibody detected the EIF4ENIF1 protein (arrow).)
Western Blot (WB)
(EIF4ENIF1 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the EIF4ENIF1 antibody detected the EIF4ENIF1 protein (arrow).)
shuttle protein for the translation initiation factor eIF4E. This
shuttle protein interacts with the importin alpha-beta complex to
mediate nuclear import of eIF4E. It is predominantly cytoplasmic;
its own nuclear import is regulated by a nuclear localization
signal and nuclear export signals. Multiple transcript variants
encoding different isoforms have been found for this gene.
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Lee, H.C., et al. Biochem. Biophys. Res. Commun. 369(4):1160-1165(2008)
Denoeud, F., et al. Genome Res. 17(6):746-759(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Uniprot Description
4E-T: Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism. Interacts with EIF4E. Interacts with importin beta only in the presence of importin alpha, suggesting a direct interaction with importin alpha. Widely expressed. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; Karyopherin; Nuclear import
Chromosomal Location of Human Ortholog: 22q11.2
Cellular Component: PML body; intracellular membrane-bound organelle; membrane; cytoplasm; nuclear speck; cytosol; nucleus
Molecular Function: protein binding; protein transporter activity
Biological Process: protein transport
Research Articles on EIF4ENIF1
Similar Products
Product Notes
The EIF4ENIF1 eif4enif1 (Catalog #AAA9202665) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 80-108. The EIF4ENIF1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EIF4ENIF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the EIF4ENIF1 eif4enif1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EIF4ENIF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
