Rabbit anti-Human EHD3 Polyclonal Antibody | anti-EHD3 antibody

EHD3 Antibody, FITC conjugated

Cat. Num. AAA7045367

• Gene Names: EHD3; PAST3
• Reactivity: Human
• Applications: ELISA
• Purity: >95%, Protein G purified
• Synonyms: EHD3; Polyclonal Antibody; EHD3 Antibody; FITC conjugated; EH domain-containing protein 3Curated; PAST homolog 3Curated; anti-EHD3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 535

• Applicable Applications for anti-EHD3 antibody: ELISA (EIA)
• Species: Human
• Immunogen: Recombinant human EH domain-containing protein 3 protein
• Conjugate: FITC
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Related Product Information for anti-EHD3 antibody

ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:25686250). In vitro causes tubulation of endocytic membranes (PubMed:24019528). Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology (PubMed:16251358, PubMed:17233914, PubMed:19139087, PubMed:23781025). Involved in the recycling of internalized D1 dopamine receptor (PubMed:21791287). Plays a role in cardiac protein trafficking probably implicating ANK2 (PubMed:20489164). Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte exitability and cardiac conduction (By similarity). In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function (By similarity). Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance (PubMed:23781025). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing (By similarity). Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with EHD1 (PubMed:25686250).

NCBI and Uniprot Product Information

• NCBI GI #: 7657056
• NCBI GeneID: 30845
• NCBI Accession #: NP_055415.1
• NCBI GenBank Nucleotide #: NM_014600.2
• UniProt Accession #: Q9NZN3; Q8N514; Q9NZB3; B4DFR5; D6W574
• Molecular Weight: 19,584 Da
• NCBI Official Full Name: EH domain-containing protein 3
• NCBI Official Synonym Full Names: EH domain containing 3
• NCBI Official Symbol: EHD3
• NCBI Official Synonym Symbols: PAST3
• NCBI Protein Information: EH domain-containing protein 3
• UniProt Protein Name: EH domain-containing protein 3
• Protein Family: EH domain-containing protein
• UniProt Gene Name: EHD3
• UniProt Entry Name: EHD3_HUMAN

Uniprot Description

EHD3: Plays a role in endocytic transport.

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: cytoplasm; endosome membrane; focal adhesion; nucleus; recycling endosome membrane

Molecular Function: nucleic acid binding; protein binding

Biological Process: blood coagulation; cilium biogenesis; endocytic recycling; protein homooligomerization; receptor recycling