Western Blot (WB)
(Western BlotPositive WB detected in: HepG2 whole cell lysate,Rat liver tissue,Rat brain tissueAll lanes: EGR2 antibody at 3.4ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 51,45 KDaObserved band size: 51 KDa)
Rabbit anti-Human, Rat EGR2 Polyclonal Antibody | anti-EGR2 antibody
EGR2 Antibody
IF: 1:50-1:200
Western Blot (WB)
(Western BlotPositive WB detected in: HepG2 whole cell lysate,Rat liver tissue,Rat brain tissueAll lanes: EGR2 antibody at 3.4ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 51,45 KDaObserved band size: 51 KDa)
Western Blot (WB)
(Western BlotPositive WB detected in: HepG2 whole cell lysate,Rat liver tissue,Rat brain tissueAll lanes: EGR2 antibody at 3.4ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 51,45 KDaObserved band size: 51 KDa)
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7051909 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunofluorescence (IF)
(Immunofluorescent analysis of Hela cells using MBS7051909 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Uniprot Description
EGR2: sequence-specific DNA-binding transcription factor. Controls systemic autoimmunity; essential for the induction of T-cell anergy. Egr2 and Egr3 induce the suppressive activity of CD4+ T cells, cooperatively inhibiting humoral immune responses by promoting TGF-¿3 secretion. Belongs to the EGR C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; DNA-binding; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 10q21.3
Cellular Component: cytoplasm; nucleus
Molecular Function: chromatin binding; protein binding; transcription factor activity; ubiquitin protein ligase binding
Biological Process: brain development; fat cell differentiation; peripheral nervous system development; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein export from nucleus; transcription from RNA polymerase II promoter
Disease: Charcot-marie-tooth Disease, Demyelinating, Type 1d; Hypertrophic Neuropathy Of Dejerine-sottas; Neuropathy, Congenital Hypomyelinating Or Amyelinating, Autosomal Recessive
Research Articles on EGR2
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Product Notes
The EGR2 egr2 (Catalog #AAA7051909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EGR2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EGR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:5000 IF: 1:50-1:200. Researchers should empirically determine the suitability of the EGR2 egr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EGR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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