Rabbit EGFL7 Polyclonal Antibody | anti-EGFL7 antibody

EGFL7 Rabbit Polyclonal

Cat. Num. AAA768898

• Gene Names: EGFL7; NEU1; ZNEU1; VE-STATIN
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: EGFL7; Polyclonal Antibody; EGFL7 Rabbit Polyclonal; anti-EGFL7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 273

• Applicable Applications for anti-EGFL7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: EGF-like-domain, multiple 7
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS768898 (EGFL7 Antibody) at dilution of 1:50)

Western Blot (WB)

(human heart tissue were subjected to SDS PAGE followed by western blot with MBS768898 (EGFL7 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 41393583
• NCBI GeneID: 51162
• NCBI Accession #: NP_958854.1
• NCBI GenBank Nucleotide #: NM_201446.2
• Molecular Weight: 29,618 Da
• NCBI Official Full Name: epidermal growth factor-like protein 7
• NCBI Official Synonym Full Names: EGF like domain multiple 7
• NCBI Official Symbol: EGFL7
• NCBI Official Synonym Symbols: NEU1; ZNEU1; VE-STATIN
• NCBI Protein Information: epidermal growth factor-like protein 7
• UniProt Protein Name: Epidermal growth factor-like protein 7
• Protein Family: Epidermal growth factor-like protein
• UniProt Gene Name: EGFL7
• UniProt Synonym Gene Names: MEGF7; EGF-like protein 7; Multiple EGF-like domains protein 7; VE-statin
• UniProt Entry Name: EGFL7_HUMAN

NCBI Description

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Uniprot Description

EGFL7: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular matrix; extracellular region; extracellular space

Molecular Function: calcium ion binding

Biological Process: angiogenesis; blood vessel development; cell adhesion; negative regulation of Notch signaling pathway; positive regulation of endothelial cell proliferation; vasculogenesis