Rabbit anti-Human EFHC2 Polyclonal Antibody | anti-EFHC2 antibody

EFHC2, NT (EFHC2, EF-hand domain-containing family member C2)

Cat. Num. AAA6013497

• Gene Names: EFHC2; dJ1158H2.1
• Reactivity: Human
• Applications: ELISA, Western Blot, Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: EFHC2; Polyclonal Antibody; NT (EFHC2; EF-hand domain-containing family member C2); Anti -EFHC2; anti-EFHC2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-EFHC2 antibody: ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Western Blot, Flow Cytometry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Flow Cytometry: 1:10-50
• Immunogen: EFHC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100~130 amino acids from the N-terminal region of human EFHC2.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of EFHC2 Antibody (N-term) in K562 cell line lysates (35ug/lane). EFHC2 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(EFHC2 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Product Categories/Family for anti-EFHC2 antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 31542743
• NCBI GeneID: 80258
• NCBI Accession #: NP_079460.2
• NCBI GenBank Nucleotide #: NM_025184.3
• UniProt Accession #: Q5JST6; Q5JST8; Q68DK4; Q8NEI0; Q9H653
• Molecular Weight: 87,397 Da
• NCBI Official Full Name: EF-hand domain-containing family member C2
• NCBI Official Synonym Full Names: EF-hand domain (C-terminal) containing 2
• NCBI Official Symbol: EFHC2
• NCBI Official Synonym Symbols: dJ1158H2.1
• NCBI Protein Information: EF-hand domain-containing family member C2
• UniProt Protein Name: EF-hand domain-containing family member C2
• Protein Family: EF-hand domain-containing family
• UniProt Gene Name: EFHC2
• UniProt Entry Name: EFHC2_HUMAN

NCBI Description

This gene encodes a protein which contains three DM10 domains and three calcium-binding EF-hand motifs. A related protein is encoded by a gene on chromosome 6. It has been suggested that both proteins are involved in the development of epilepsy (PMID: 15258581, 16112844) and that this gene may be associated with fear recognition in individuals with Turner syndrome. [provided by RefSeq, Aug 2011]

Uniprot Description

EFHC2: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: Xp11.3

Molecular Function: calcium ion binding