Western Blot (WB)
(EDN2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EDN2 antibody detected the EDN2 protein (arrow).)
Rabbit EDN2 Polyclonal Antibody | anti-EDN2 antibody
EDN2 Antibody (C-term)
Western Blot (WB)
(EDN2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EDN2 antibody detected the EDN2 protein (arrow).)
Western Blot (WB)
(EDN2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EDN2 antibody detected the EDN2 protein (arrow).)
Western Blot (WB)
(Western blot analysis of EDN2 (arrow) using rabbit polyclonal EDN2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EDN2 gene.)
Western Blot (WB)
(Western blot analysis of EDN2 (arrow) using rabbit polyclonal EDN2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the EDN2 gene.)
family of secretory vasoconstrictive peptides. The preproprotein is
processed to a short mature form which functions as a ligand for
the endothelin receptors that initiate intracellular signaling
events. This gene product is involved in a wide range of biological
processes, such as hypertension and ovulation. [provided by
RefSeq].
Darrah, R., et al. Physiol. Genomics 41(1):71-77(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
Wiesmann, F., et al. Breast Cancer Res. 11 (3), R34 (2009) :
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
EDN2: Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: extracellular space; extracellular region
Molecular Function: hormone activity
Biological Process: neutrophil chemotaxis; vasoconstriction; inositol phosphate-mediated signaling; regulation of systemic arterial blood pressure by endothelin; cytokine and chemokine mediated signaling pathway; positive regulation of the force of heart contraction by chemical signal; calcium-mediated signaling; positive regulation of leukocyte chemotaxis; positive regulation of heart rate; thermoregulation; vein smooth muscle contraction; hormonal regulation of the force of heart contraction; prostaglandin biosynthetic process; macrophage chemotaxis; macrophage activation; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; regulation of vasoconstriction; positive regulation of cell proliferation; positive regulation of smooth muscle contraction; alveolus development; artery smooth muscle contraction
Research Articles on EDN2
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Product Notes
The EDN2 edn2 (Catalog #AAA9213876) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 107-136. The EDN2 Antibody (C-term) reacts with Human (Predicted Reactivity: Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's EDN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the EDN2 edn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EDN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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