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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human prostate cancer using MBS768855 (ECHS1 antibody) at dilution of 1:100)

Rabbit ECHS1 Polyclonal Antibody | anti-ECHS1 antibody

ECHS1 Rabbit Polyclonal

Gene Names
ECHS1; SCEH; ECHS1D
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
ECHS1; Polyclonal Antibody; ECHS1 Rabbit Polyclonal; anti-ECHS1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
290
Applicable Applications for anti-ECHS1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Immunogen
Enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS768855 (ECHS1 antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human prostate cancer using MBS768855 (ECHS1 antibody) at dilution of 1:100)

Western Blot (WB)

(human liver tissue were subjected to SDS PAGE followed by western blot with MBS768855 (ECHS1 antibody) at dilution of 1:1200)

Western Blot (WB) (human liver tissue were subjected to SDS PAGE followed by western blot with MBS768855 (ECHS1 antibody) at dilution of 1:1200)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,387 Da
NCBI Official Full Name
enoyl-CoA hydratase, mitochondrial
NCBI Official Synonym Full Names
enoyl-CoA hydratase, short chain, 1, mitochondrial
NCBI Official Symbol
ECHS1
NCBI Official Synonym Symbols
SCEH; ECHS1D
NCBI Protein Information
enoyl-CoA hydratase, mitochondrial
UniProt Protein Name
Enoyl-CoA hydratase, mitochondrial
Protein Family
UniProt Gene Name
ECHS1
UniProt Synonym Gene Names
SCEH
UniProt Entry Name
ECHM_HUMAN

NCBI Description

The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. [provided by RefSeq, Jul 2008]

Uniprot Description

ECHS1: Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Belongs to the enoyl-CoA hydratase/isomerase family.

Protein type: Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - fatty acid elongation in mitochondria; Mitochondrial; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - lysine degradation; EC 4.2.1.17; Carbohydrate Metabolism - butanoate; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - fatty acid; Lyase; Carbohydrate Metabolism - propanoate

Chromosomal Location of Human Ortholog: 10q26.2-q26.3

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: enoyl-CoA hydratase activity; protein binding

Biological Process: fatty acid beta-oxidation

Disease: Mitochondrial Short-chain Enoyl-coa Hydratase 1 Deficiency

Research Articles on ECHS1

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Product Notes

The ECHS1 echs1 (Catalog #AAA768855) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ECHS1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ECHS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ECHS1 echs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECHS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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