Goat EAR2 Polyclonal Antibody | anti-Ear2 antibody
EAR2 (Nuclear Receptor Subfamily 2 Group F Member 6, V-erbA-related Protein 2, EAR-2, NR2F6, ERBAL2)
Gene Names
Ear2; 2; ECP; EAR-2; ECP 2; EAR-13; Rnase2
Reactivity
Bovine, Canine, Human, Mouse, Porcine, Rat
Applications
ELISA
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
EAR2; Polyclonal Antibody; EAR2 (Nuclear Receptor Subfamily 2 Group F Member 6; V-erbA-related Protein 2; EAR-2; NR2F6; ERBAL2); Anti -EAR2 (Nuclear Receptor Subfamily 2 Group F Member 6; anti-Ear2 antibody
Host
Goat
Reactivity
Bovine, Canine, Human, Mouse, Porcine, Rat
Clonality
Polyclonal
Specificity
Recognizes EAR2. Species sequence homology: Canine, human, mouse, porcine, bovine and rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Applicable Applications for anti-Ear2 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: ELISA: 1:32,000
Dilution: ELISA: 1:32,000
Immunogen
Synthetic peptide corresponding to C-STFNWPYGSGQ, from EAR2, at C-terminal (NP_005225.2).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Ear2 antibody
NR2F6, also known as Nuclear receptor subfamily 2 group F member 6, is a nuclear protein belonging to the nuclear hormone receptor family and NR2 subfamily with a nuclear receptor DNA-binding domain. NR2F6 is a nuclear receptor involved in action regulation of the transcription of the GNRH1 gene. It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription. NR2F6 is required early in the development of the locus ceruleus (LC), thus in some way contributing to the regulation of the forebrain clock, at least in part, through targeted release of noradrenalin into the cortical area.
Product Categories/Family for anti-Ear2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,620 Da
NCBI Official Full Name
eosinophil cationic protein 2
NCBI Official Synonym Full Names
eosinophil-associated, ribonuclease A family, member 2
NCBI Official Symbol
Ear2
NCBI Official Synonym Symbols
2; ECP; EAR-2; ECP 2; EAR-13; Rnase2
NCBI Protein Information
eosinophil cationic protein 2; RNase 3-2; ribonuclease 3-2; eosinophil-associated ribonuclease 2; eosinophil-derived neurotoxin, liver; eosinophil-associated ribonuclease 13; eosinophil secondary granule ribonuclease 2
UniProt Protein Name
Eosinophil cationic protein 2
Protein Family
UniProt Gene Name
Ear2
UniProt Synonym Gene Names
Rnase2; ECP 2; EAR-2; RNase 3-2
UniProt Entry Name
ECP2_MOUSE
Uniprot Description
Function: Cytotoxin and helminthotoxin with ribonuclease activity. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Subcellular location: Cytoplasmic granule
By similarity. Note: Matrix of eosinophil's large specific granule
By similarity.
Domain: The N-terminal region is necessary for mediating chemotactic activity.
Sequence similarities: Belongs to the pancreatic ribonuclease family.
Research Articles on Ear2
Similar Products
Product Notes
The Ear2 ear2 (Catalog #AAA649627) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The EAR2 (Nuclear Receptor Subfamily 2 Group F Member 6, V-erbA-related Protein 2, EAR-2, NR2F6, ERBAL2) reacts with Bovine, Canine, Human, Mouse, Porcine, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EAR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA: 1:32,000. Researchers should empirically determine the suitability of the Ear2 ear2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EAR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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