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Western Blot (WB) (Western blot analysis of E Cadherin expression in HEK293T (A); A431 (B); MCF7 (C); mouse kidney (D); rat kidney (E) whole cell lysates.)

Rabbit E Cadherin Polyclonal Antibody | anti-CDHE antibody

E Cadherin Antibody

Gene Names
CDH1; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
E Cadherin; Polyclonal Antibody; E Cadherin Antibody; Purified Polyclonal E Cadherin Antibody; Polyclonal E Cadherin antibody; Anti-E Cadherin antibody; CDHE antibody; UVO antibody; Cadherin-1 antibody; CAM 120/80 antibody; Epithelial cadherin antibody; E-cadherin antibody; Uvomorulin antibody; CD324 antibody; anti-CDHE antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of E Cadherin protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
827
Applicable Applications for anti-CDHE antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:1000
IHC: 1:100-1:200
Immunogen
E Cadherin antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human E Cadherin as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of E Cadherin expression in HEK293T (A); A431 (B); MCF7 (C); mouse kidney (D); rat kidney (E) whole cell lysates.)

Western Blot (WB) (Western blot analysis of E Cadherin expression in HEK293T (A); A431 (B); MCF7 (C); mouse kidney (D); rat kidney (E) whole cell lysates.)
Related Product Information for anti-CDHE antibody
E Cadherin is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role.
Product Categories/Family for anti-CDHE antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
999
NCBI Official Full Name
E-cadherin, partial
NCBI Official Synonym Full Names
cadherin 1
NCBI Official Symbol
CDH1
NCBI Official Synonym Symbols
UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
NCBI Protein Information
cadherin-1

NCBI Description

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]

Research Articles on CDHE

Similar Products

Product Notes

The CDHE (Catalog #AAA5314137) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's E Cadherin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:1000 IHC: 1:100-1:200. Researchers should empirically determine the suitability of the CDHE for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "E Cadherin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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