Western Blot (WB)
(Western Blot analysis of Mouse-Brain cells using Phospho-Dynamin I (S778) Polyclonal Antibody)
Rabbit Dynamin I Polyclonal Antibody | anti-DNM1 antibody
Dynamin I (Phospho-Ser778) Polyclonal Antibody
ELISA: 1:20000
Not yet tested in other applications
Western Blot (WB)
(Western Blot analysis of Mouse-Brain cells using Phospho-Dynamin I (S778) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Mouse-Brain cells using Phospho-Dynamin I (S778) Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
DYN1: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within the presynaptic compartment and may participate in specialized neuronal functions such as rapid synaptic vesicle recycling. Part of a protein network that controls nucleation of actin from membranes. Contains one PH domain.
Protein type: Motility/polarity/chemotaxis; Motor; Vesicle; EC 3.6.5.5; Hydrolase; Microtubule-binding
Chromosomal Location of Human Ortholog: 9q34
Cellular Component: microtubule; membrane coat; plasma membrane
Molecular Function: protein C-terminus binding; GTPase activity; identical protein binding; protein binding; GTP binding; protein complex binding; nitric-oxide synthase binding; protein kinase binding
Biological Process: axon guidance; receptor-mediated endocytosis; endosome organization and biogenesis; receptor internalization; ephrin receptor signaling pathway; endocytosis
Disease: Epileptic Encephalopathy, Early Infantile, 31
Research Articles on DNM1
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Product Notes
The DNM1 dnm1 (Catalog #AAA9410561) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dynamin I (Phospho-Ser778) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Dynamin I can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Western blotting: 1:500 - 1:2000 ELISA: 1:20000 Not yet tested in other applications. Researchers should empirically determine the suitability of the DNM1 dnm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dynamin I, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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