Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Dynamin 3 Polyclonal Antibody | anti-DNM3 antibody
Polyclonal Antibody to Dynamin 3 (DNM3)
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-1:5000
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control. Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded brain tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded brain tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Uniprot Description
DYN3: a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Concentrates within dendritic spine tips of the postsynaptic compartment and interacts with mGluR5 and Homer. May play a role in dendritic spine morphogenesis and remodeling.
Protein type: EC 3.6.5.5; Hydrolase; Microtubule-binding; Mitochondrial; Motility/polarity/chemotaxis; Motor; Vesicle
Chromosomal Location of Human Ortholog: 1q24.3
Cellular Component: axon; dendritic spine; dendritic spine head; extracellular exosome; Golgi apparatus; microtubule; mitochondrial membrane; perinuclear region of cytoplasm; photoreceptor inner segment; postsynaptic density; postsynaptic endocytic zone membrane
Molecular Function: GTP binding; GTPase activity; microtubule binding; nitric-oxide synthase binding; protein binding; type 1 metabotropic glutamate receptor binding; type 5 metabotropic glutamate receptor binding
Biological Process: dynamin family protein polymerization involved in mitochondrial fission; endocytosis; filopodium assembly; mitochondrial fission; positive regulation of filopodium formation; postsynaptic neurotransmitter receptor internalization; synaptic vesicle budding from presynaptic endocytic zone membrane; synaptogenesis
Research Articles on DNM3
Similar Products
Product Notes
The DNM3 dnm3 (Catalog #AAA2033718) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Dynamin 3 (DNM3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Dynamin 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-1:5000. Researchers should empirically determine the suitability of the DNM3 dnm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dynamin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
