Western Blot (WB)
(Western Blot analysis of DUSP4 expression in transfected 293T cell line by DUSP4 polyclonal antibody. Lane 1: DUSP4 transfected lysate (43kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human DUSP4 Polyclonal Antibody | anti-DUSP4 antibody
DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase hVH2, HVH2, Mitogen-activated Protein Kinase Phosphatase 2, MAP Kinase Phosphatase 2, MKP2, MKP-2, TYP, VH2) (PE)
Western Blot (WB)
(Western Blot analysis of DUSP4 expression in transfected 293T cell line by DUSP4 polyclonal antibody. Lane 1: DUSP4 transfected lysate (43kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of DUSP4 expression in transfected 293T cell line by DUSP4 polyclonal antibody. Lane 1: DUSP4 transfected lysate (43kD). Lane 2: Non-transfected lysate.)
Testing Data
(Proximity Ligation Analysis (PLA) of protein-protein interactions between DUSP4 and MAPK9 HeLa cells were stained with DUSP4 rabbit purified polyclonal 1:1200 and MAPK9 mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex)
Testing Data
(Proximity Ligation Analysis (PLA) of protein-protein interactions between DUSP4 and MAPK9 HeLa cells were stained with DUSP4 rabbit purified polyclonal 1:1200 and MAPK9 mouse monoclonal antibody 1:50. Signals were detected by 30 Detection Kit 613 (red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008]
Research Articles on DUSP4
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Product Notes
The DUSP4 (Catalog #AAA6376732) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase hVH2, HVH2, Mitogen-activated Protein Kinase Phosphatase 2, MAP Kinase Phosphatase 2, MKP2, MKP-2, TYP, VH2) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DUSP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DUSP4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUSP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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