Western Blot (WB)
(DSCR1L1 Antibody (Q21) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).)
Rabbit anti-Human, mouse DSCR1L1 Polyclonal Antibody | anti-RCAN2 antibody
DSCR1L1 Antibody (N-term)
Western Blot (WB)
(DSCR1L1 Antibody (Q21) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).)
Western Blot (WB)
(DSCR1L1 Antibody (Q21) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).)
Western Blot (WB)
(DSCR1L1 Antibody (Q21) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).)
Western Blot (WB)
(DSCR1L1 Antibody (Q21) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DSCR1L1 antibody detected the DSCR1L1 protein (arrow).)
Immunohistochemistry (IHC)
(DSCR1L1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DSCR1L1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(DSCR1L1 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DSCR1L1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(DSCR1L1 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(DSCR1L1 Antibody (N-term) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Fuentes, J.J., et al., Hum. Mol. Genet. 9(11):1681-1690 (2000).
Strippoli, P., et al., Genomics 64(3):252-263 (2000).
Miyazaki, T., et al., J. Biol. Chem. 271(24):14567-14571 (1996).
Cao, X., et al., Biochem. J. 367 (PT 2), 459-466 (2002) (): ().
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
RCAN2: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. Belongs to the RCAN family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 6p12.3
Molecular Function: nucleotide binding
Biological Process: calcineurin-NFAT signaling pathway; short-term memory; response to oxidative stress; locomotion during locomotory behavior
Research Articles on RCAN2
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Product Notes
The RCAN2 rcan2 (Catalog #AAA9203105) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 6-37. The DSCR1L1 Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DSCR1L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the RCAN2 rcan2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSCR1L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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