Western Blot (WB)
(Western blot analysis of DSCR1 (pS108) expression in HEK293T (A), Jurkat (B), NIH3T3 (C), CT26 (D) whole cell lysates.)
Rabbit DSCR1 Polyclonal Antibody | anti-DSCR1 antibody
Anti-DSCR1 (pS108) Phospho Antibody
Gene Names
RCAN1; CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
Reactivity
Human, Mouse, Rat, Bovine, Sheep
Applications
Western Blot
Purity
Purified by immunogen affinity chromatography.
Synonyms
DSCR1; Polyclonal Antibody; Anti-DSCR1 (pS108) Phospho Antibody; ADAPT78; CSP1; DSC1; Calcipressin-1; Adapt78; Down syndrome critical region protein 1; Myocyte-enriched calcineurin-interacting protein 1; MCIP1; Regulator of calcineurin 1; anti-DSCR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Sheep
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of DSCR1 (pS108) protein.
Purity/Purification
Purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Sequence Length
171
Applicable Applications for anti-DSCR1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DSCR1.
Preparation and Storage
Upon delivery aliquot and store at-20 degree C for one year. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of DSCR1 (pS108) expression in HEK293T (A), Jurkat (B), NIH3T3 (C), CT26 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of DSCR1 (pS108) expression in HEK293T (A), Jurkat (B), NIH3T3 (C), CT26 (D) whole cell lysates.)
Related Product Information for anti-DSCR1 antibody
Rabbit polyclonal antibody to DSCR1 (pS108)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,767 Da
NCBI Official Full Name
calcipressin-1 isoform d
NCBI Official Synonym Full Names
regulator of calcineurin 1
NCBI Official Symbol
RCAN1
NCBI Official Synonym Symbols
CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
NCBI Protein Information
calcipressin-1
UniProt Protein Name
Calcipressin-1
UniProt Gene Name
RCAN1
UniProt Synonym Gene Names
ADAPT78; CSP1; DSC1; DSCR1; MCIP1
NCBI Description
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Uniprot Description
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A (PubMed:12809556). Could play a role during central nervous system development ().
Research Articles on DSCR1
Similar Products
Product Notes
The DSCR1 rcan1 (Catalog #AAA8304214) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-DSCR1 (pS108) Phospho Antibody reacts with Human, Mouse, Rat, Bovine, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's DSCR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the DSCR1 rcan1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DSCR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
