Western Blot (WB)
(Western BlotPositive WB detected in: A549 whole cell lysateAll lanes: DRD1 antibody at 3.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 50 KDaObserved band size: 50 KDa)
Rabbit anti-Human DRD1 Polyclonal Antibody | anti-DRD1 antibody
DRD1 Antibody
Western Blot (WB)
(Western BlotPositive WB detected in: A549 whole cell lysateAll lanes: DRD1 antibody at 3.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 50 KDaObserved band size: 50 KDa)
Western Blot (WB)
(Western BlotPositive WB detected in: A549 whole cell lysateAll lanes: DRD1 antibody at 3.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 50 KDaObserved band size: 50 KDa)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human lung cancer using MBS7048049 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of human lung cancer using MBS7048049 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of A549 cells using MBS7048049 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC)
(Immunofluorescent analysis of A549 cells using MBS7048049 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
DRD1: a G-protein coupled receptor.One of the five types (D1 to D5) of receptors for dopamine. The most abundant dopamine receptor in the central nervous system. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Interacts with calcyon.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 5q35.1
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine receptor activity; protein binding
Biological Process: adenylate cyclase activation; adult walking behavior; cerebral cortex GABAergic interneuron migration; dopamine metabolic process; dopamine receptor, adenylate cyclase activating pathway; dopamine receptor, phospholipase C activating pathway; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; learning; mating behavior; positive regulation of cAMP biosynthetic process; positive regulation of cell migration; positive regulation of potassium ion transport; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of synaptic transmission, glutamatergic; prepulse inhibition; regulation of dopamine uptake; response to drug; synaptic transmission, dopaminergic; synaptogenesis; transmission of nerve impulse; visual learning
Research Articles on DRD1
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Product Notes
The DRD1 drd1 (Catalog #AAA7048049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DRD1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DRD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the DRD1 drd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DRD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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