Western Blot (WB)
((1ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat DRAK2 Polyclonal Antibody | anti-STK17B antibody
Goat anti-DRAK2 Antibody
Gene Names
STK17B; DRAK2
Reactivity
Tested: Human; Expected from sequence similarity: Human, Dog
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
DRAK2; Polyclonal Antibody; Goat anti-DRAK2 Antibody; STK17B; serine/threonine kinase 17b; death-associated protein kinase-related 2; serine/threonine kinase 17b (apoptosis-inducing); STK17B antibody; serine/threonine kinase 17b antibody; DRAK2 antibody; death-associated protein kinase-related 2 antibody; serine/threonine kinase 17b (apoptosis-inducing) antibody; anti-STK17B antibody
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human, Dog
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
HSVRSSEDKTSK
Sequence Length
372
Applicable Applications for anti-STK17B antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 45kDa band observed in lysates of cell line MOLT4 (calculated MW of 42.3kDa according to NP_004217.1). Recommended concentration: 1-3ug/ml.
Western Blot: Approx 45kDa band observed in lysates of cell line MOLT4 (calculated MW of 42.3kDa according to NP_004217.1). Recommended concentration: 1-3ug/ml.
Immunogen
Peptide with sequence C-HSVRSSEDKTSK, from the internal region of the protein sequence according to NP_004217.1.
Epitope
Internal region
Note
This antiboyd may cross-react with rat STK17B (GeneID: 170904).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Western Blot (WB)
((1ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,344 Da
NCBI Official Full Name
serine/threonine-protein kinase 17B
NCBI Official Synonym Full Names
serine/threonine kinase 17b
NCBI Official Symbol
STK17B
NCBI Official Synonym Symbols
DRAK2
NCBI Protein Information
serine/threonine-protein kinase 17B
UniProt Protein Name
Serine/threonine-protein kinase 17B
Protein Family
UniProt Gene Name
STK17B
UniProt Synonym Gene Names
DRAK2
UniProt Entry Name
ST17B_HUMAN
Uniprot Description
DRAK2: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; CAMK group; DAPK family
Chromosomal Location of Human Ortholog: 2q32.3
Cellular Component: actin cytoskeleton; ER-Golgi intermediate compartment; nucleus; plasma membrane
Molecular Function: ATP binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process: apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation
Research Articles on STK17B
Similar Products
Product Notes
The STK17B stk17b (Catalog #AAA422141) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-DRAK2 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's DRAK2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 45kDa band observed in lysates of cell line MOLT4 (calculated MW of 42.3kDa according to NP_004217.1). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the STK17B stk17b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: HSVRSSEDKT SK. It is sometimes possible for the material contained within the vial of "DRAK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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