Western Blot (WB)
(WB Suggested Anti-DPY19L2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart)
Rabbit DPY19L2 Polyclonal Antibody | anti-DPY19L2 antibody
DPY19L2 antibody - middle region
Western Blot (WB)
(WB Suggested Anti-DPY19L2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart)
Western Blot (WB)
(WB Suggested Anti-DPY19L2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart)
Target Description: The exact functions of DPY19L2 remain unknown.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9). [provided by RefSeq, Dec 2011]
Uniprot Description
DPY19L2: Required during spermatogenesis for sperm head elongation and acrosome formation. Defects in DPY19L2 are the cause of spermatogenic failure type 9 (SPGF9). An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoon. Deletions in DPY19L2 are probably the major cause of SPGF9. Belongs to the dpy-19 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 12q14.2
Cellular Component: integral to membrane; nuclear inner membrane; nucleus
Molecular Function: mannosyltransferase activity
Biological Process: multicellular organismal development; protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan; spermatid development
Disease: Spermatogenic Failure 9
Research Articles on DPY19L2
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Product Notes
The DPY19L2 dpy19l2 (Catalog #AAA3212359) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DPY19L2 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DPY19L2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the DPY19L2 dpy19l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: IIGEFNNLPQ EELLQWIKYS TTSDAVFAGA MPTMASIKLS TLHPIVNHPH. It is sometimes possible for the material contained within the vial of "DPY19L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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