Immunohistochemistry (IHC)
(Immunohistochemical of paraffin-embedded human prostate cancer using MBS768735 (DOK4 antibody) at dilution of 1:50)
Rabbit DOK4 Polyclonal Antibody | anti-DOK4 antibody
DOK4 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemical of paraffin-embedded human prostate cancer using MBS768735 (DOK4 antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemical of paraffin-embedded human prostate cancer using MBS768735 (DOK4 antibody) at dilution of 1:50)
NCBI and Uniprot Product Information
Uniprot Description
DOK4: docking proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in Ret-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of Ret in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. Interacts with Ret and TIE2. Interaction with Ret is mediated through the PTB domain and requires phosphorylation of Ret Y1062.
Protein type: Adaptor/scaffold; Cell development/differentiation
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: intracellular
Molecular Function: insulin receptor binding; protein binding; receptor signaling protein activity
Biological Process: MAPKKK cascade; nervous system development; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on DOK4
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Product Notes
The DOK4 dok4 (Catalog #AAA768735) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DOK4 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DOK4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DOK4 dok4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOK4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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