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Western Blot (WB) (Western blot analysis of DOCK11 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.)

Rabbit DOCK11 Polyclonal Antibody | anti-DOCK11 antibody

DOCK11 Antibody

Gene Names
DOCK11; ACG; ZIZ2; bB128O4.1
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
DOCK11; Polyclonal Antibody; DOCK11 Antibody; Purified Polyclonal DOCK11 Antibody; Polyclonal DOCK11 antibody; Anti-DOCK11 antibody; ZIZ2 antibody; Dedicator of cytokinesis protein 11 antibody; Activated Cdc42-associated guanine nucleotide exchange factor antibody; ACG antibody; Zizimin-2 antibody; anti-DOCK11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of DOCK11 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
2073
Applicable Applications for anti-DOCK11 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
DOCK11 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DOCK11 as the immunogen
Cross-Reactivity
Mouse, Rat, Pig
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of DOCK11 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.)

Western Blot (WB) (Western blot analysis of DOCK11 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.)
Related Product Information for anti-DOCK11 antibody
DOCK11 exhibits the same domain arrangement as other members of the DOCK-D/Zizimin subfamily and shares the highest level of sequence identity with Dock9. It contains a DHR2 domain which mediates GEF activity and a DHR1 domain which may interact with membrane phospholipids. It also contains an N-terminal PH domain which may be involved in its recruitment to the plasma membrane.
Product Categories/Family for anti-DOCK11 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
dedicator of cytokinesis protein 11
NCBI Official Synonym Full Names
dedicator of cytokinesis 11
NCBI Official Symbol
DOCK11
NCBI Official Synonym Symbols
ACG; ZIZ2; bB128O4.1
NCBI Protein Information
dedicator of cytokinesis protein 11
UniProt Protein Name
Dedicator of cytokinesis protein 11
UniProt Gene Name
DOCK11
UniProt Synonym Gene Names
ZIZ2; ACG
UniProt Entry Name
DOC11_HUMAN

Uniprot Description

DOCK11: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Belongs to the DOCK family.

Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: cytosol

Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding

Biological Process: small GTPase mediated signal transduction; blood coagulation

Similar Products

Product Notes

The DOCK11 dock11 (Catalog #AAA5315801) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DOCK11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the DOCK11 dock11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOCK11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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