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Western Blot (WB) (Western Blot analysis in A549 cell line lysates (35ug/lane) usingMBS6000115. This demonstrates that MBS6000115 detected the DNASE1L1 protein (arrow).)

Rabbit anti-Human DNASE1L1 Polyclonal Antibody | anti-DNASE1L1 antibody

DNASE1L1, ID (DNASE1L1, DNAS1L1, DNL1L, Deoxyribonuclease-1-like 1, DNase X, Deoxyribonuclease I-like 1, Muscle-specific DNase I-like, XIB) (Biotin)

Gene Names
DNASE1L1; XIB; G4.8; DNL1L; DNASEX; DNAS1L1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A and Peptide Affinity Chromatography.
Synonyms
DNASE1L1; Polyclonal Antibody; ID (DNASE1L1; DNAS1L1; DNL1L; Deoxyribonuclease-1-like 1; DNase X; Deoxyribonuclease I-like 1; Muscle-specific DNase I-like; XIB) (Biotin); XIB; anti-DNASE1L1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human DNASE1L1.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-DNASE1L1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 177-204 in the central region of human DNASE1L1, UniProt Accession #P49184.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in A549 cell line lysates (35ug/lane) usingMBS6000115. This demonstrates that MBS6000115 detected the DNASE1L1 protein (arrow).)

Western Blot (WB) (Western Blot analysis in A549 cell line lysates (35ug/lane) usingMBS6000115. This demonstrates that MBS6000115 detected the DNASE1L1 protein (arrow).)
Related Product Information for anti-DNASE1L1 antibody
This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Product Categories/Family for anti-DNASE1L1 antibody
References
1. Bailey, S.D., et al. Diabetes Care (2010) In press: 2. Ueki, M., et al. Electrophoresis 31(12):2063-2069(2010). 3. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). 4. Shiokawa, D., et al. Biochem. J. 392 (PT 3), 511-517 (2005). 5. Malferrari, G., et al. Exp. Mol. Pathol. 66(2):123-130(1999).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,893 Da
NCBI Official Full Name
deoxyribonuclease-1-like 1
NCBI Official Synonym Full Names
deoxyribonuclease I-like 1
NCBI Official Symbol
DNASE1L1
NCBI Official Synonym Symbols
XIB; G4.8; DNL1L; DNASEX; DNAS1L1
NCBI Protein Information
deoxyribonuclease-1-like 1; DNase X; DNase I-like 1; DNase I-like, muscle-specific
UniProt Protein Name
Deoxyribonuclease-1-like 1
Protein Family
UniProt Gene Name
DNASE1L1
UniProt Synonym Gene Names
DNAS1L1; DNL1L; DNase I-like 1
UniProt Entry Name
DNSL1_HUMAN

Uniprot Description

DNASE1L1: a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]

Protein type: EC 3.1.21.-; Deoxyribonuclease

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: endoplasmic reticulum; nucleus

Molecular Function: endodeoxyribonuclease activity, producing 5'-phosphomonoesters; DNA binding; deoxyribonuclease activity; endodeoxyribonuclease activity

Biological Process: DNA metabolic process; DNA catabolic process, endonucleolytic

Similar Products

Product Notes

The DNASE1L1 dnase1l1 (Catalog #AAA6292929) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNASE1L1, ID (DNASE1L1, DNAS1L1, DNL1L, Deoxyribonuclease-1-like 1, DNase X, Deoxyribonuclease I-like 1, Muscle-specific DNase I-like, XIB) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DNASE1L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DNASE1L1 dnase1l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNASE1L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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